Results 51 to 60 of about 769,896 (315)
Computational Mechanism Design: A Call to Arms [PDF]
, 2003 Game theory has developed powerful tools for analyzing decision making in systems with multiple autonomous actors. These tools, when tailored to computational settings, provide a foundation for building multiagent software systems.
Jennings, N. R. +3 more
core
Finite-size correction for slab supercell calculations of materials with spontaneous polarization
npj Computational Materials, 2021 The repeated slab approach has become a de facto standard to accurately describe surface properties of materials by density functional theory calculations with periodic boundary conditions.
Su-Hyun Yoo +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Computational engineering design under uncertainty: an aircraft conceptual design perspective [PDF]
, 2009 Presented in this thesis is a novel methodology for aircraft design optimization in the presence of uncertainty, with emphasis on the conceptual design stage.
Padulo, Mattia
core
Computational Chemistry and Catalysis: Prediction and Design [PDF]
, 2023 The combination of computational chemistry and catalysis is an insightful approach that can be utilized to predict and design a catalyst, its function and the outcome of the catalytic chemical reaction that this catalyst activates in terms of activity ...
Salah-Eddine Stiriba
core +1 more source
Computational Design Thinking and Thinking Design Computing [PDF]
Conference Proceedings, 2019 In alignment with the rapid advancement of cyber-physical technologies in an information age, we are faced with complex problems that go beyond the kinds of challenges that designers had to deal with in the past. For many of these challenges we do not have established theories, methods, or tools to solve the problems.
openaire +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
A Brief Review of Computational Product Design: A Brand Identity Approach
Machines, 2023 On the way to designing customized products as one of the core activities of Industry 4.0, the strategy of computational design emerges as a unique design process due to its flexibility and simplicity.
Athanasios Manavis +2 more
doaj +1 more source