Results 61 to 70 of about 769,896 (315)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Co-Design und agentenbasierte Methoden für mehrgeschossige Holzbausysteme [PDF]
Timber, the most widely used natural material in the construction industry, can sequester carbon as it grows and store it in the built environment.
Orozco, Luis
core +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Creative Approaches in Product Design [PDF]
, 2009 Organised by: Cranfield UniversityThis research paper presents a knowledge-based system for creative design tools (CDT). The main aim of the developed CDT system is to provide designers with a flexible creative design environment to enhance their ...
Abdalla, Hassan S., Salah, F.
core
Co-Design-Methoden für kollektive robotische Konstruktionssysteme in der Architektur [PDF]
Collective robotic construction (CRC) is a newly defined field that addresses questions of the application of multiple robot systems (MRS) in the Architecture, Engineering, and Construction (AEC) industry.
Leder, Samuel
core +1 more source
Computational design of passive grippers
ACM Transactions on Graphics, 2022 This work proposes a novel generative design tool for passive grippers---robot end effectors that have no additional actuation and instead leverage the existing degrees of freedom in a robotic arm to perform grasping tasks. Passive grippers are used because they offer interesting trade-offs between cost and capabilities.
Milin Kodnongbua +4 more
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Architektonische Potentiale robotischer Fertigung im Holzbau : Strategien für interdisziplinäre Innovation in Herstellungs- und Entwurfsmethoden [PDF]
, 2022 This thesis investigates the impact of innovation in robotic manufacturing and computational design on the architectural and tectonic possibilities of timber construction. Until recently, the digitalization of manufacturing and design has mostly resulted
Krieg, Oliver David
core +1 more source
Numerical tools for computational design of acoustic metamaterials [PDF]
, 2020 The notion of metamaterials as artificially engineered structures designed to obtain specific material properties, typically unachievable in naturally occurring materials, has captured the attention of the scientific and industrial communities. Among the
Oliver Olivella, Xavier +3 more
core +2 more sources
npj Computational MaterialsWe conduct a systematic investigation of the role of Hubbard U corrections in electronic structure calculations of two-dimensional (2D) materials containing 3d transition metals. Specifically, we use density functional theory (DFT) with the PBE and PBE+U
Sahar Pakdel +2 more
doaj +1 more source