Results 31 to 40 of about 70,729 (246)

A Review on the Mixing Quality of Static Mixers

ChemEngineering
Static mixers are widely used devices for efficient fluid mixing, homogenization, and enhancement of heat transfer, with applications ranging from chemical processing and pharmaceutical manufacturing to wastewater treatment.
Lukas von Damnitz, Denis Anders
doaj   +1 more source

Robotic Pectoral Fin Thrust Vectoring Using Weighted Gait Combinations

Applied Bionics and Biomechanics, 2012
A method was devised to vector propulsion of a robotic pectoral fin by means of actively controlling fin surface curvature. Separate flapping fin gaits were designed to maximize thrust for each of three different thrust vectors: forward, reverse, and ...
John S. Palmisano, Jason D. Geder, Ravi Ramamurti, William C. Sandberg, Banahalli Ratna   +4 more
doaj   +1 more source

CFD Simulation of UV Disinfection Reactor for Applesauce with a Low UV Absorption Coefficient

Journal of Chemical and Petroleum Engineering, 2014
In this study, a Computational Fluid Dynamics (CFD) model was developed to evaluate ultraviolet disinfection applesauce reactor. To simulate UV reactors, three sets of equations, including hydrodynamics, radiation and species mass conservation were ...
Seyed Hassan Hashemabadi, Farkhondeh Ghaderzadeh, Fariborz Taghipour   +2 more
doaj   +1 more source

Effect of louver baffles installation on hydrodynamics of bubbling fluidization in biomass gasifier

Scientific Reports, 2022
Biomass gasification by a bubbling bed gasifier has been a promising process to produce fuels from biomass. However, the performance is limited by gas aggregation in the gasifier.
Kiattikhoon Phuakpunk, Benjapon Chalermsinsuwan, Suttichai Assabumrungrat   +2 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

MPAS‐Ocean Simulation Quality for Variable‐Resolution North American Coastal Meshes

Journal of Advances in Modeling Earth Systems, 2020
Climate model components utilizing unstructured meshes enable variable resolution, regionally enhanced simulations within global domains. Here we investigate the relationship between mesh quality and simulation statistics using the JIGSAW unstructured ...
Kristin E. Hoch, Mark R. Petersen, Steven R. Brus, Darren Engwirda, Andrew F. Roberts, Kevin L. Rosa, Phillip J. Wolfram   +6 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Comparative numerical studies of the mechanical efficiency of sandwich-panels with different non-/auxetic prismatic and lattice cores subjected to ballistic loading

Forces in Mechanics
Civil as well as military facilities, vehicles and applications must increasingly meet higher safety standards to ensure the highest possible protection against extraordinary stresses such as ballistic and/or air-blast loading.
Marcel Walkowiak, Denis Anders, Ulf Reinicke   +2 more
doaj   +1 more source