Results 91 to 100 of about 9,181,016 (294)

Impact of valve morphology, hypertension and age on aortic wall properties in patients with coarctation: a two-centre cross-sectional study

BMJ Open, 2020
Objective We aimed to investigate the combined effects of arterial hypertension, bicuspid aortic valve disease (BAVD) and age on the distensibility of the ascending and descending aortas in patients with aortic coarctation.Design Cross-sectional study ...
Felix Berger, Stephan Schubert, Niky Ghorbani, Vivek Muthurangu, Abbas Khushnood, Leonid Goubergrits, Sarah Nordmeyer, Joao Filipe Fernandes, Chong-Bin Lee, Kilian Runte, Sophie Roth, Sebastian Kelle, Titus Kuehne, Marcus Kelm   +13 more
doaj   +1 more source

Autofocusing Algorithm for Pixel-Super-Resolved Lensfree On-Chip Microscopy

Frontiers in Physics, 2021
In recent years, lensfree on-chip microscopy has developed into a promising and powerful computational optical microscopy technique that allows for wide-field, high-throughput microscopic imaging without using any lenses.
Yumin Wu, Yumin Wu, Yumin Wu, Yumin Wu, Linpeng Lu, Linpeng Lu, Linpeng Lu, Linpeng Lu, Jialin Zhang, Jialin Zhang, Jialin Zhang, Jialin Zhang, Zhuoshi Li, Zhuoshi Li, Zhuoshi Li, Zhuoshi Li, Chao Zuo, Chao Zuo, Chao Zuo, Chao Zuo   +19 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Single-shot super-resolved fringe projection profilometry (SSSR-FPP): 100,000 frames-per-second 3D imaging with deep learning

Light: Science & Applications
To reveal the fundamental aspects hidden behind a variety of transient events in mechanics, physics, and biology, the highly desired ability to acquire three-dimensional (3D) images with ultrafast temporal resolution has been long sought.
Bowen Wang, Wenwu Chen, Jiaming Qian, Shijie Feng, Qian Chen, Chao Zuo   +5 more
doaj   +1 more source

Reading Responses To Journal Articles, Computational Emulation Of Published Research [PDF]

, 2018
Students responded to sets of journal articles in computational optics and imaging every week. Articles investigated scientific questions, visualization of scientific data, ethical questions, and international collaborative projects (such as the Event ...
Ganapati, Vidya
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Principal component analysis for three-dimensional structured illumination microscopy (PCA-3DSIM)

Light: Science & Applications
Three-dimensional structured illumination microscopy (3DSIM) is an essential super-resolution imaging technique for visualizing volumetric subcellular structures at the nanoscale, capable of doubling both lateral and axial resolution beyond the ...
Jiaming Qian, Weiyi Xia, Yuxia Huang, Jing Feng, Qian Chen, Chao Zuo   +5 more
doaj   +1 more source

Single-shot compressed ultrafast photography: a review [PDF]

, 2020
Compressed ultrafast photography (CUP) is a burgeoning single-shot computational imaging technique that provides an imaging speed as high as 10 trillion frames per second and a sequence depth of up to a few hundred frames.
Cao, Fengyan, Ding, Pengpeng, Gao, Liang, He, Yilin, Jia, Tianqing, Liang, Jinyang, Qi, Dalong, Sun, Zhenrong, Wang, Lihong V., Yang, Chengshuai, Yao, Jiali, Zhang, Shian   +11 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Efficient implementation of the adaptive scale pixel decomposition algorithm

, 2016
Context. Most popular algorithms in use to remove the effects of a telescope's point spread function (PSF) in radio astronomy are variants of the CLEAN algorithm.
Bhatnagar, S., Rau, U., Zhang, L., Zhang, M.   +3 more
core   +1 more source