Results 41 to 50 of about 271,448 (263)

Lens-free on-chip 3D microscopy based on wavelength-scanning Fourier ptychographic diffraction tomography

Light: Science & Applications
Lens-free on-chip microscopy is a powerful and promising high-throughput computational microscopy technique due to its unique advantage of creating high-resolution images across the full field-of-view (FOV) of the imaging sensor.
Xuejuan Wu, Ning Zhou, Yang Chen, Jiasong Sun, Linpeng Lu, Qian Chen, Chao Zuo   +6 more
doaj   +1 more source

High-resolution transport-of-intensity quantitative phase microscopy with annular illumination

Scientific Reports, 2017
For quantitative phase imaging (QPI) based on transport-of-intensity equation (TIE), partially coherent illumination provides speckle-free imaging, compatibility with brightfield microscopy, and transverse resolution beyond coherent diffraction limit ...
Chao Zuo, Jiasong Sun, Jiaji Li, Jialin Zhang, Anand Asundi, Qian Chen   +5 more
doaj   +1 more source

Evolution of cortical geometry and its link to function, behaviour and ecology

Nature Communications, 2023
Studies in comparative neuroanatomy and of the fossil record demonstrate the influence of socio-ecological niches on the morphology of the cerebral cortex, but have led to oftentimes conflicting theories about its evolution.
Ernst Schwartz, Karl-Heinz Nenning, Katja Heuer, Nathan Jeffery, Ornella C. Bertrand, Roberto Toro, Gregor Kasprian, Daniela Prayer, Georg Langs   +8 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Learned denoising with simulated and experimental low-dose CT data

Scientific Reports
Like in many other research fields, recent developments in computational imaging have focused on developing machine learning (ML) approaches to tackle its main challenges.
Maximilian B. Kiss, Ander Biguri, Carola-Bibiane Schönlieb, K. Joost Batenburg, Felix Lucka   +4 more
doaj   +1 more source

In-silico trial of intracranial flow diverters replicates and expands insights from conventional clinical trials

Nature Communications, 2021
In-silico trials rely on virtual populations and interventions simulated using patient-specific models and may offer a solution to lower costs. Here, the authors present the flow diverter performance assessment in-silico trial, which models the treatment
Ali Sarrami-Foroushani, Toni Lassila, Michael MacRaild, Joshua Asquith, Kit C. B. Roes, James V. Byrne, Alejandro F. Frangi   +6 more
doaj   +1 more source

Scattering-Assisted Computational Imaging

Photonics, 2022
Imaging objects hidden behind an opaque shelter provides a crucial advantage when physically going around the obstacle is impossible or dangerous. Previous methods have demonstrated that is possible to reconstruct the image of a target hidden from view ...
Yiwei Sun, Xiaoyan Wu, Jianhong Shi, Guihua Zeng   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Single-shot super-resolved fringe projection profilometry (SSSR-FPP): 100,000 frames-per-second 3D imaging with deep learning

Light: Science & Applications
To reveal the fundamental aspects hidden behind a variety of transient events in mechanics, physics, and biology, the highly desired ability to acquire three-dimensional (3D) images with ultrafast temporal resolution has been long sought.
Bowen Wang, Wenwu Chen, Jiaming Qian, Shijie Feng, Qian Chen, Chao Zuo   +5 more
doaj   +1 more source