Results 31 to 40 of about 4,253,827 (311)
Easy-to-use libraries such as scikit-learn have accelerated the adoption and application of machine learning (ML) workflows and data-driven methods. While many of the algorithms implemented in these libraries originated in specific scientific fields ...
Philip Loche +7 more
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Computer modelling of monoamine oxidases [PDF]
The article summarized results of studies on active site structures of monoamine oxidases (MAO) performed in the Institute of Biomedical Chemistry (Russia) by computer modelling approaches. MAO, catalyzing the reaction of oxidative deamination of major neurotransmitter monoamines, exists in two highly homologous forms, MAO A and MAO B, distinguished by
A V, Veselovsky +2 more
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Simulation of Fire with a Gas Kinetic Scheme on Distributed GPGPU Architectures
The simulation of fire is a challenging task due to its occurrence on multiple space-time scales and the non-linear interaction of multiple physical processes. Current state-of-the-art software such as the Fire Dynamics Simulator (FDS) implements most of
Stephan Lenz +2 more
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Withasomniferol C, a new potential SARS-CoV-2 main protease inhibitor from the Withania somnifera plant proposed by in silico approaches [PDF]
Exploring potent herbal medicine candidates is a promising strategy for combating a pandemic in the present global health crisis. In Ayurveda (a traditional medicine system in India), Withania somnifera (WS) is one of the most important herbs and it has ...
Shivananada Kandagalla +5 more
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Computational modeling of epilepsy [PDF]
SummaryWith the rapid rise in our knowledge about the structural and functional properties of neuronal microcircuits and the exponentially increasing power of computers, it has become possible to closely integrate experimental findings with large‐scale, anatomically and biophysically realistic computational simulations of control and epileptic neuronal
Marianne, Case, Ivan, Soltesz
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Synchronizability of Discrete Nonlinear Systems: A Master Stability Function Approach
In recent times, studies on discrete nonlinear systems received much attention among researchers because of their potential applications in real-world problems.
Mohanasubha Ramasamy +4 more
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In-Silico Design of Novel Glucagon-Like Peptide 1 Mutants as Candidate for New Peptide Agonist Drugs
The binding of glucagon-like peptide 1 (GLP-1) incretin hormone and its receptor GLP-1R plays an important role in the human body. The GLP-1 acts as the insulin secretion stimulator through a GLP-1R agonist activation to avoid the type 2 diabetes ...
Tony Sumaryada +4 more
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Models of Representation in Computational Intelligence [Guest Editorial] [PDF]
Computational Intelligence (CI) provides a set of powerful tools to effectively tackle complex computational tasks: global optimization methods (e.g., evolutionary computation, swarm intelligence), machine learning (e.g., neural networks), fuzzy ...
Manzoni, Luca +7 more
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Mathematical modeling and computational intelligence in engineering applications
This book brings together a rich selection of studies in mathematical modeling and computational intelligence, with application in several fields of engineering, like automation, biomedical, chemical, civil, electrical, electronic, geophysical and ...
Llanes Santiago, Orestes +5 more
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Background Although a safe and effective yellow fever vaccine was developed more than 80 years ago, several issues regarding its use remain unclear. For example, what is the minimum dose that can provide immunity against the disease?
Carla R. B. Bonin +3 more
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