Results 31 to 40 of about 364,009 (218)
This article presents studies related to the driving and control of the switched reluctance generator in order to enhance its efficiency. This type of electrical machine is an option for wind energy conversion systems, favoring the generation of ...
Wanderson R. H. Araujo +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
In order to design viscoelastic sandwich structures used as passive damping treatment, many aspects should be considered. In all methods available in the literature to model Viscoelastic Materials (VEM) a crucial step is the determination of the complex ...
Felippe Filho W. N., Barbosa F.
doaj +1 more source
Traffic Sign Recognition (TSR) is one of the many utilities made possible by embedded systems with internet connections. Through the usage of vehicular cameras, it’s possible to capture and classify traffic signs in real time with Artificial Intelligence
Vanessa Dalborgo +7 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
360-Degree Tri-Modal Scanning: Engineering a Modular Multi-Sensor Platform for Semantic Enrichment of BIM Models [PDF]
Point clouds, image data, and corresponding processing algorithms are intensively investigated to create and enrich Building Information Models (BIM) with as-is information and maintain their value across the building lifecycle.
F. C. Collins +4 more
doaj +1 more source

