Results 31 to 40 of about 2,430,102 (287)

Exploratory study to identify radiomics classifiers for lung cancer histology

Frontiers in Oncology, 2016
Background: Radiomics can quantify tumor phenotypic characteristics non-invasively by applying feature algorithms to medical imaging data. In this study of lung cancer patients, we investigated the association between radiomic features and the tumor ...
Weimiao eWu, Weimiao eWu, Chintan eParmar, Chintan eParmar, Chintan eParmar, Patrick eGrossmann, Patrick eGrossmann, John eQuackenbush, John eQuackenbush, Philippe eLambin, Johan eBussink, Raymond eMak, Hugo eAerts, Hugo eAerts   +13 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Does Exploring Computer Science Increase Computer Science Enrollment?

, 2018
This study investigated the impact of the Exploring Computer Science (ECS) program on the likelihood that students of all races and gender would pursue further computer science coursework in high school. ECS is designed to foster deep engagement through equitable inquiry around computer science concepts.
Steven McGee, Randi McGee-Tekula, Jennifer Duck, Lucia Dettori, Don Yanek, Andrew M. Rasmussen, Ronald I. Greenberg, Dale F, Reed   +7 more
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Improving Interoperability in Scientific Computing via MaRDI Open Interfaces

Journal of Open Research Software
MaRDI Open Interfaces is a software project aimed at improving reuse and interoperability in scientific computing by alleviating the difficulties of crossing boundaries between different programming languages, such as C, Julia, or Python, in which ...
Dmitry I. Kabanov, Stephan Rave, Mario Ohlberger   +2 more
doaj   +1 more source

Using Graphing Calculators to Integrate Mathematics and Science [PDF]

, 1997
The computational, graphing, statistical and programming capabilities of today’s graphing calculators make it possible for teachers and students to explore aspects of functions and investigate real-world situations in ways that were previously ...
Garofalo, J., Pullano, F.
core   +1 more source

Norman Julius Zabusky OBITUARY [PDF]

, 2018
Norman Julius Zabusky, who laid the foundations for several critical advancements in nonlinear science and experimental mathematics, died of idiopathic pulmonary fibrosis on 5 February 2018 in Beersheba, Israel.
Campbell, David K., Newell, Alan C., Porter, Mason A.   +2 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Re-run, Repeat, Reproduce, Reuse, Replicate: Transforming Code into Scientific Contributions

Frontiers in Neuroinformatics, 2018
Scientific code is different from production software. Scientific code, by producing results that are then analyzed and interpreted, participates in the elaboration of scientific conclusions.
Fabien C. Y. Benureau, Fabien C. Y. Benureau, Fabien C. Y. Benureau, Nicolas P. Rougier, Nicolas P. Rougier, Nicolas P. Rougier   +5 more
doaj   +1 more source