Results 61 to 70 of about 8,980,708 (398)

A systematic review of computational thinking in science classrooms

open access: yesStudies in science education, 2021
Computational thinking (CT) has been described as an essential skill that should be learned by everyone and can, therefore, be included in their skill set.
A. Ogegbo, U. Ramnarain
semanticscholar   +1 more source

From computational science to Internetics: Integration of science with computer science [PDF]

open access: yesMathematics and Computers in Simulation, 2000
Abstract We describe how our world dominated by science and scientists has been changed and will be revolutionized by technologies moving with internet time. Computers have always been well-used tools but in the beginning only the science counted and little credit or significance was attached to any computing activities associated with scientific ...
openaire   +2 more sources

Mathematical modeling based on ordinary differential equations: A promising approach to vaccinology

open access: yesHuman Vaccines & Immunotherapeutics, 2017
New contributions that aim to accelerate the development or to improve the efficacy and safety of vaccines arise from many different areas of research and technology.
Carla Rezende Barbosa Bonin   +3 more
doaj   +1 more source

Human social sensing is an untapped resource for computational social science

open access: yesNature, 2021
The ability to ‘sense’ the social environment and thereby to understand the thoughts and actions of others allows humans to fit into their social worlds, communicate and cooperate, and learn from others’ experiences.
M. Galesic   +8 more
semanticscholar   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Ex Machina: Analytical platforms, Law and the Challenges of Computational Legal Science

open access: yesFuture Internet, 2018
Over the years, computation has become a fundamental part of the scientific practice in several research fields that goes far beyond the boundaries of natural sciences.
Nicola Lettieri   +7 more
doaj   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

The DEMO Quasisymmetric Stellarator

open access: yesEnergies, 2010
The NSTAB nonlinear stability code solves differential equations in conservation form, and the TRAN Monte Carlo test particle code tracks guiding center orbits in a fixed background, to provide simulations of equilibrium, stability, and transport in ...
Geoffrey B. McFadden, Paul R. Garabedian
doaj   +1 more source

Ten Research Challenge Areas in Data Science [PDF]

open access: yesarXiv, 2020
Although data science builds on knowledge from computer science, mathematics, statistics, and other disciplines, data science is a unique field with many mysteries to unlock: challenging scientific questions and pressing questions of societal importance.
arxiv  

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

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