Results 61 to 70 of about 2,948,294 (361)

Rethinking resource allocation in science

Ecology and Society, 2019
Many funding agencies rely on grant proposal peer review to allocate scientific funding, i.e., researchers compete for funding by submitting proposals that are reviewed and ranked by committees of their peers.
Johan Bollen, Stephen R. Carpenter, Jane Lubchenco, Marten Scheffer   +3 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Ex Machina: Analytical platforms, Law and the Challenges of Computational Legal Science

Future Internet, 2018
Over the years, computation has become a fundamental part of the scientific practice in several research fields that goes far beyond the boundaries of natural sciences.
Nicola Lettieri, Antonio Altamura, Rosalba Giugno, Alfonso Guarino, Delfina Malandrino, Alfredo Pulvirenti, Francesco Vicidomini, Rocco Zaccagnino   +7 more
doaj   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

For a heterodox computational social science

Big Data & Society, 2021
The proliferation of digital data has been the impetus for the emergence of a new discipline for the study of social life: ‘computational social science’.
Petter Törnberg, Justus Uitermark
doaj   +1 more source

Integration of Python into Science Teacher Education, Developing Computational Problem Solving and Using Information and Communication Technologies Competencies of Pre-service Science Teachers

Informatics in Education, 2022
This study reports the findings of a program that aims to develop pre-service science teachers’ computational problem-solving skills and views on using information and communications technology in science education.
Kaan BATI
doaj   +1 more source

Towards a computational transportation science

Journal of Spatial Information Science, 2011
This report of a community activity, a Dagstuhl Seminar earlier in 2010, postulates the need for a computational transportation science, as the science behind intelligent transportation systems.
Stephan Winter, Monika Sester, Ouri Wolfson, Glenn Geers   +3 more
doaj   +3 more sources

AiiDA: Automated Interactive Infrastructure and Database for Computational Science

, 2015
Computational science has seen in the last decades a spectacular rise in the scope, breadth, and depth of its efforts. Notwithstanding this prevalence and impact, it is often still performed using the renaissance model of individual artisans gathered in ...
Cepellotti, Andrea, Kozinsky, Boris, Marzari, Nicola, Pizzi, Giovanni, Sabatini, Riccardo   +4 more
core   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Natural Language Processing at the School of Information Studies for Africa [PDF]

, 2005
The lack of persons trained in computational linguistic methods is a severe obstacle to making the Internet and computers accessible to people all over the world in their own languages.
Eriksson, Gunnar, Fourla, Athanassia, Gambäck, Björn   +2 more
core   +1 more source