Results 41 to 50 of about 109,371 (286)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A Workflow for Software Development within Computational Epidemiology [PDF]
, 2011 A critical investigation into computational models developed for studying the spread of communicable disease is presented. The case in point is a spatially explicit micro-meso-macro model for the entire Swedish population built on registry data, thus far
Baki Cakici +6 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Big data in social and psychological science: Theoretical and methodological issues
, 2017 Big data presents unprecedented opportunities to understand human behavior on a large scale. It has been increasingly used in social and psychological research to reveal individual differences and group dynamics.
CHAN, Sarah Hian May +5 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Towards reproducibility in online social network research
, 2015 This work was supported by the Engineering and Physical Sciences Research Council [grant number EP/J500549/1].The challenge of conducting reproducible computational research is acknowledged across myriad disciplines from biology to computer science.
Hutton, Luke, Henderson, Tristan
core +1 more source
2016 Computational Social Science Workshop Program
, 2016 Program of events from the 2016 Computational Social Science ...
Computational Social Science Workshop Organizing Committee
core +1 more source
Quantifying crowd size with mobile phone and Twitter data [PDF]
Royal Society Open Science, 2015 Being able to infer the number of people in a specific area is of extreme importance for the avoidance of crowd disasters and to facilitate emergency evacuations.
Federico Botta +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A virtual reality experiment to study pedestrian perception of future street scenarios
Scientific ReportsThe current allocation of street space is based on expected vehicular peak-hour flows. Flexible and adaptive use of this space can respond to changing needs.
Javier Argota Sánchez-Vaquerizo +6 more
doaj +1 more source