Results 51 to 60 of about 39,144,787 (249)
Contribution-Based Grouping under Noise
Many real-world mechanisms are “noisy” or “fuzzy”, that is the institutions in place to implement them operate with non-negligible degrees of imprecision and error.
Heinrich H. Nax +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Collective navigation of complex networks: Participatory greedy routing
Many networks are used to transfer information or goods, in other words, they are navigated. The larger the network, the more difficult it is to navigate efficiently.
Kaj-Kolja Kleineberg, Dirk Helbing
doaj +1 more source
Attitudes towards Participation in a Passive Data Collection Experiment
In this paper, we present the results of an exploratory study conducted in Hungary using a factorial design-based online survey to explore the willingness to participate in a future research project based on active and passive data collection via ...
Bence Ságvári +2 more
doaj +1 more source
07431 Executive Summary – Computational Issues in Social Choice [PDF]
Computational social choice is an interdisciplinary field of study at the interface of social choice theory and computer science, with knowledge flowing in either direction.
Endriss, Ulle +3 more
core +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Los Angeles County Social Survey, 1993 (LACSS)
The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
How voting rules impact legitimacy
Collective action is essential for addressing the grand challenges of our time. However, for such action to be successful, decision-making processes must be perceived as legitimate. In this study, we investigate the legitimacy of different voting methods.
Carina I. Hausladen +5 more
doaj +1 more source

