Results 51 to 60 of about 109,371 (286)
Adaptive nowcasting of influenza outbreaks using Google searches [PDF]
Royal Society Open Science, 2014 Seasonal influenza outbreaks and pandemics of new strains of the influenza virus affect humans around the globe. However, traditional systems for measuring the spread of flu infections deliver results with one or two weeks delay. Recent research suggests
Tobias Preis, Helen Susannah Moat
doaj +1 more source
Attitudes towards Participation in a Passive Data Collection Experiment
Sensors, 2021 In this paper, we present the results of an exploratory study conducted in Hungary using a factorial design-based online survey to explore the willingness to participate in a future research project based on active and passive data collection via ...
Bence Ságvári +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
From calculations to reasoning: history, trends, and the potential of Computational Ethnography and Computational Social Anthropology [PDF]
, 2023 The domains of 'computational social anthropology' and 'computational ethnography' refer to the computational processing or computational modelling of data for anthropological or ethnographic research.
Doerr, Martin +3 more
core +1 more source
Ethics and Interdisciplinarity in Computational Social Science
Methodological Innovations, 2012 During the last few years a growing amount of content produced by Internet users has become publicly available online. These data come from a variety of places, including popular social web services like Facebook and Twitter, consumer services like ...
Fabio Giglietto, Luca Rossi
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Contribution-Based Grouping under Noise
Games, 2017 Many real-world mechanisms are “noisy” or “fuzzy”, that is the institutions in place to implement them operate with non-negligible degrees of imprecision and error.
Heinrich H. Nax +3 more
doaj +1 more source
Five Hundred Days of Farsi Twitter
Journal of Quantitative Description: Digital Media, 2022 International media was quick to dub the Iranian Green Movement a “Twitter revolution” when it erupted in the summer of 2009. State violence against protestors was captured in real time and broadcast worldwide on social media, providing an early example
Layla Hashemi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source