Results 61 to 70 of about 837,732 (325)

Ethics and Interdisciplinarity in Computational Social Science

Methodological Innovations, 2012
During the last few years a growing amount of content produced by Internet users has become publicly available online. These data come from a variety of places, including popular social web services like Facebook and Twitter, consumer services like ...
Fabio Giglietto, Luca Rossi
doaj   +1 more source

Adaptive nowcasting of influenza outbreaks using Google searches [PDF]

Royal Society Open Science, 2014
Seasonal influenza outbreaks and pandemics of new strains of the influenza virus affect humans around the globe. However, traditional systems for measuring the spread of flu infections deliver results with one or two weeks delay. Recent research suggests
Tobias Preis, Helen Susannah Moat
doaj   +1 more source

Five Hundred Days of Farsi Twitter

Journal of Quantitative Description: Digital Media, 2022
International media was quick to dub the Iranian Green Movement a “Twitter revolution” when it erupted in the summer of 2009. State violence against protestors was captured in real time and broadcast worldwide on social media, providing an early example
Layla Hashemi, Steven Wilson, Constanza Sanhueza   +2 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Contribution-Based Grouping under Noise

Games, 2017
Many real-world mechanisms are “noisy” or “fuzzy”, that is the institutions in place to implement them operate with non-negligible degrees of imprecision and error.
Heinrich H. Nax, Ryan O. Murphy, Stefano Duca, Dirk Helbing   +3 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Thinking spatially in computational social science

EPJ Data Science
Deductive and theory-driven research starts by asking questions. Finding tentative answers to these questions in the literature is next. It is followed by gathering, preparing and modelling relevant data to empirically test these tentative answers ...
Aliakbar Akbaritabar
doaj   +1 more source

Agriculture, Food and Nutrition Security: Concept, Datasets and Opportunities for Computational Social Science Applications [PDF]

, 2023
T.S. Amjath-Babu, Santiago Lopez Riadura, Timothy J. Krupnik   +2 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Collective navigation of complex networks: Participatory greedy routing

Scientific Reports, 2017
Many networks are used to transfer information or goods, in other words, they are navigated. The larger the network, the more difficult it is to navigate efficiently.
Kaj-Kolja Kleineberg, Dirk Helbing
doaj   +1 more source