Results 21 to 30 of about 311,562 (267)

A decade of dengue disease burden in Africa (2013–2023): a systematic review

Travel Medicine and Infectious Disease
Background: Dengue is a major mosquito-borne disease worldwide. The epidemiological trends of the disease in Africa over the past decade remain unclear. This review aims to provide insight into the epidemiological trends of dengue in Africa from 2013 to ...
Gaspary O. Mwanyika, Monika Moir, Abdualmoniem O. Musa, Jenicca Poongavanan, Graeme Dor, Eduan Wilkinson, Cheryl Baxter, Tulio de Oliveira, Houriiyah Tegally   +8 more
doaj   +1 more source

Understanding the Transmission Dynamics of the Chikungunya Virus in Africa

Pathogens
The Chikungunya virus (CHIKV) poses a significant global public health concern, especially in Africa. Since its first isolation in Tanzania in 1953, CHIKV has caused recurrent outbreaks, challenging healthcare systems in low-resource settings.
Yajna Ramphal, Houriiyah Tegally, James Emmanuel San, Martina Larissa Reichmuth, Marije Hofstra, Eduan Wilkinson, Cheryl Baxter, CLIMADE Consortium, Tulio de Oliveira, Monika Moir   +9 more
doaj   +1 more source

A systematic review of integrating computational thinking in early childhood education

Computers and Education Open, 2023
Computational thinking education has become an increasingly popular topic among practitioners and researchers. However, rare is known how to effectively teach and learn computational thinking in early childhood education.
Jiahong Su, Weipeng Yang
doaj   +1 more source

Effect of Learning Style on Non-Programmed Computational Thinking Activities

Engineering Proceedings, 2023
As information explosion and algorithms are proliferated in the digital age, computational thinking becomes more critical. Nevertheless, most activities that promote computational thinking are always presented in a programming or block language, which ...
Yen-Yun Chen, Shih-Wen Su, Li-Xian Chen, Chia-Hung Liao, Shyan-Ming Yuan   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Alignment-free viral sequence classification at scale

BMC Genomics
Background The rapid increase in nucleotide sequence data generated by next-generation sequencing (NGS) technologies demands efficient computational tools for sequence comparison.
Daniel J. van Zyl, Marcel Dunaiski, Houriiyah Tegally, Cheryl Baxter, Tulio de Oliveira, Joicymara S. Xavier, The INFORM Africa research study group   +6 more
doaj   +1 more source

The Cognitive Basis of Computation: Putting Computation in Its Place [PDF]

, 2018
The mainstream view in cognitive science is that computation lies at the basis of and explains cognition. Our analysis reveals that there is no compelling evidence or argument for thinking that brains compute.
Hutto, Daniel D., Myin, Erik, Peeters, Anco, Zahnoun, Farid   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A quantum leaky integrate-and-fire spiking neuron and network

npj Quantum Information
Quantum machine learning is in a period of rapid development and discovery, however it still lacks the resources and diversity of computational models of its classical complement.
Dean Brand, Francesco Petruccione
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source