Results 41 to 50 of about 51,743 (307)

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

Refining an understanding of computational thinking

open access: yes, 2014
This paper identifies aspects of computational thinking and proposes a description that meets the needs of teachers and academics reflecting upon the developing UK curriculum.
Woollard, John, Selby, Cynthia
core  

A Review of Reviews on Computational Thinking Assessment in Higher Education

open access: yes, 2022
There is an urgent need for educating the next generation of learners with digital tools and making use of digital practices and skills. Education on computational thinking (CT) is widespread around the world with a dominant focus on K- 12. Recently also
Zhang, X. (author)   +1 more
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Computational thinking: the developing definition

open access: yes, 2013
Since Jeanette Wing’s use of the term computational thinking in 2006, various discussions have arisen seeking a robust definition of the phrase.
Woollard, John, Selby, Cynthia
core  

Ubiquity symposium: Computation and Computational Thinking [PDF]

open access: yesUbiquity, 2011
In this ninth piece to the Ubiquity symposium discussing What is computation? Alfred V. Aho shares his views about the importance of computational thinking in answering the question. --Editor
openaire   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

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