Results 41 to 50 of about 314,779 (317)

Relationships: computational thinking, pedagogy of programming, and Bloom’s Taxonomy

, 2015
This study explores the relationship between computational thinking, teaching programming, and Bloom’s Taxonomy. Data is collected from teachers, academics, and professionals, purposively selected because of their knowledge of the topics of problem ...
Bell T., Butler M., Computing at School Working Group, Du Boulay B., Glaser B., Jenkins T., Prosser J., Thompson E., Wing J.   +8 more
core   +1 more source

Foreign objects? Web content management systems, journalistic cultures and the ontology of software [PDF]

, 2014
Research on ‘digital’ journalism has focused largely on online news, with comparatively less interest in the longer-term implications of software and computational technologies.
Rodgers, Scott
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Conserved recombination patterns across hepatitis B genotypes: a retrospective study

Virology Journal
Hepatitis B virus (HBV) infection is a major public health concern, as chronic HBV infection can lead to liver cirrhosis and increase a person’s risk of developing hepatocellular carcinoma (HCC). HBV has been classified into ten genotypes (A to J). Here,
Derek Tshiabuila, James E. San, Eduan Wilkinson, Graeme Dor, Houriiyah Tegally, Tongai G. Maponga, Marion Delphin, Philippa C. Matthews, Darren P. Martin, Cheryl Baxter, Tulio de Oliveira   +10 more
doaj   +1 more source

Research questions and approaches for computational thinking curricula design [PDF]

, 2017
Teaching computational thinking (CT) is argued to be necessary but also admitted to be a very challenging task. The reasons for this, are: i) no general agreement on what computational thinking is; ii) no clear idea nor evidential support on how to teach
Berki , Eleni, Grigoriadou, Kira, Tiensuu , Aleksi, Valtanen , Juri   +3 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Dolutegravir rollout for treatment of HIV with a focus on advanced disease and tuberculosis coinfection: findings from rural KwaZulu-Natal, South Africa (2019–2023)

AIDS Research and Therapy
Background While Dolutegravir (DTG) containing antiretroviral therapy (ART) has become the preferred regimen for people living with HIV (PLHIV), the pace and equity of its adoption, especially among subgroups with tuberculosis (TB) symptoms and advanced ...
Reuben Christopher Moyo, Larisse Bolton, Elphas Luchemo Okango, Margot Otto, Nthoesele Letoao, Peter Suwirakwenda Nyasulu, Frank Tanser   +6 more
doaj   +1 more source

Computational Thinking und Kontextorientierung.

Medienimpulse, 2020
Je nach Perspektive wird in der digitalen Bildung über digitale Medien, über Medienbildung, über informationstechnische Grundbildung, über Informatik, Problemlösefähigkeiten, Schlüsselkompetenzen und technische Allgemeinbildung gesprochen.
Michael Steiner, Klaus Himpsl-Gutermann
doaj   +1 more source

Breaking the addition addiction: creating the conditions for knowing-to act in early algebra [PDF]

, 2009
We use data from a teaching experiment with a group of eight years old students to explore the potential of examining number sentences to promote relational thinking.
Ambrose, Rebecca, Castro, Encarnación, Castro, Enrique, Molina, Marta   +3 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source