Results 51 to 60 of about 311,562 (267)
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Defining a new 21st century skill-computational thinking: concepts and trends [PDF]
, 2018 Computational Thinking is a skill that guides the 21th century individual in the problems experienced during daily life and it has an ever-increasing significance. Multifarious definitions were attempted to explain the concept of Computational Thinking.
Haseski, Halil İbrahim +2 more
core +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Cosmological constant from canonical transformation in quantum cosmology
Nuclear Physics BWe explore the introduction of the cosmological constant via canonical transformations in cosmology. We consider the Wheeler-DeWitt equation for the cold dark matter (CDM) universe and we construct the Hamilton-Jacobi action for the ΛCDM model, where Λ ...
Andronikos Paliathanasis
doaj +1 more source
Hiding in Plain Sight: Identifying Computational Thinking in the Ontario Elementary School Curriculum [PDF]
, 2017 Given a growing digital economy with complex problems, demands are being made for education to address computational thinking (CT) – an approach to problem solving that draws on the tenets of computer science.
Beckett, Danielle +3 more
core +3 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
The “Telephone Game” effect in modern gravity research
European Physical Journal C: Particles and FieldsTriggered by some recent studies within the framework of nonmetricity gravity, I discuss how the basic information regarding the equivalence of the gravitational theories forming the “Trinity of Gravity” has been lost in parts of the literature.
Andronikos Paliathanasis
doaj +1 more source
RED. Revista de Educación a Distancia, 2020 New technological tools, technology-based services and support are being introduced into our daily lives faster than ever. Among these technological advances robotic technology has increased dramatically in recent years, the same as its inclusion in ...
Raidell Avello +2 more
doaj +1 more source
Computational thinking – back to the future [PDF]
, 2017 Computational Thinking is regarded as a gift from Computer Science to other discipline areas, a digital literacy skill and a cornerstone of the computing programme of study has been delivered as part of the National Curriculum in English Schools since ...
Boulton, H, Csizmadia, A
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source