Results 161 to 170 of about 2,703,446 (282)

Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li, Jiri Aubrecht, Tatyana Y. Doktorova, Danyel Jennen, J. Christopher Corton, Roland Froetschl, Roman Mezencev, Carole L. Yauk   +7 more
wiley   +1 more source

Evaluating the Enantioselective Neurotoxicity of Organophosphorus Pollutant Dioxabenzofos: Mechanistic Studies Employing Cellular, Molecular, and Computational Toxicology Assays. [PDF]

ACS Omega
He ZC, Zhang T, Lu XF, Li R, Mei Q, Wang QZ, Ding F, Peng W.   +7 more
europepmc   +1 more source

Incidence and prehospital management of convulsive status epilepticus in Martinique, a French Caribbean territory

Epilepsia Open, EarlyView.
Abstract Objective Status epilepticus (SE) is an acute complication that can either occur in the course of epilepsy, or reflect an acute neurological or systemic disorder. SE incidence and associated mortality vary across regions and studied populations.
Florian Negrello, Alexis Fremery, Jonathan Florentin, Sylvie Merle, Vianney Aquilina, Yannick Brouste, Dabor Resiere, Rishika Banydeen, Papa Gueye   +8 more
wiley   +1 more source

Nanoinformatics 2010 Program [PDF]

, 2010
Baker, Nathan A, Chaka, Anne, Cohen, Yoram, Colvin, Vicki, Fritts, Martin, Geraci, Charles L., Hoover, Mark D, Ku, Sharon, Kulinowski, Kristen M, Lippell, Phil, Luo, James, McLennan, Michael, Morse, Jeffrey, Ostraat, Michele L, Rajan, Krishna, Reznik-Zellen, Rebecca, Schad, Peter, Tuominen, Mark T.   +17 more
core  

Comparing Transcriptomic Responses to Chemicals Across Six Species Using the EcoToxChip RNASeq Database

Environmental Toxicology and Chemistry, EarlyView.
Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal, Jessica Ewald, Doug Crump, Jessica Head, Markus Hecker, Natacha Hogan, Jianguo Xia, Niladri Basu   +7 more
wiley   +1 more source

Toxicity assessment of four pharmaceuticals in aquatic environment before and after ferrate(VI) treatment [PDF]

, 2018
Jiang, Jia-Qian, Patibandla, Srinath, Shu, Xinhua   +2 more
core   +1 more source

Computational Toxicology Methods in Chemical Library Design and High-Throughput Screening Hit Validation. [PDF]

Methods Mol Biol, 2018
Hevener KE.
europepmc   +1 more source

Machine Learning Approaches for GC–MS Data Interpretation in Flavour and Fragrance Analysis

Flavour and Fragrance Journal, EarlyView.
The review explores machine learning integration in GC‐MS data analysis for the fragrance and flavour industry, highlighting recent advances and techniques in a context constrained by data scarcity and intellectual property concerns. ABSTRACT This review explores the integration of machine learning (ML) in the analysis of mass spectrometry data ...
Jean‐Baptiste Coffin, Romain Krafft, Sylvain Antoniotti, Sébastien Fiorucci   +3 more
wiley   +1 more source

Integrated Anatomical, Chemical, Biological and Computational Studies Approach of Myrcia sylvatica (G. Mey) DC. A Multifaceted Insight Into a Promising Amazonian Species

Flavour and Fragrance Journal, EarlyView.
This study presents an integrated anatomical, chemical, biological, and computational analysis of Myrcia sylvatica, revealing key bioactive compounds with antioxidant and toxicological potential, and identifying spathulenol and globulol as promising acetylcholinesterase inhibitors with favourable pharmacokinetic properties. ABSTRACT Myrcia sylvatica (G.
Eliza de Jesus Barros dos Santos, Zelina Ataíde Correia, Ely Simone Cajueiro Gurgel, Leonardo Souza da Costa, Mabrouk Horchani, Hayet Edziri, Ravendra Kumar, Anderson de Santana Botelho, Karyme do Socorro de Souza Vilhena, Eloisa Helena de Aguiar Andrade, Mozaniel Santana de Oliveira   +10 more
wiley   +1 more source

Integrated In Vitro, In Vivo, and In Silico Study Reveals Gut‐Protective Effects of Myricitrin From Chinese Bayberry Leaves

Food Frontiers, EarlyView.
High‐purity myricitrin from Chinese bayberry leaves alleviates colonic inflammation by preserving epithelial barrier integrity and reshaping gut microbiota composition. ABSTRACT Polyphenols have been widely recognized for their ability to modulate the host inflammatory response and orchestrate the intestinal microenvironment.
Ji‐Min Lv, Wei Quan, Xiao‐Hua Cheng, Jing Zhu, Aliyu Idris Muhammad, Wang‐Ting Zhou, Xing‐Jiang Qi, Chong‐De Sun   +7 more
wiley   +1 more source