Results 11 to 20 of about 69,485 (336)

Advancing Computational Toxicology by Interpretable Machine Learning. [PDF]

Environ Sci Technol, 2023
Jia X, Wang T, Zhu H.
europepmc   +3 more sources

Navigating the Minefield of Computational Toxicology and Informatics: Looking Back and Charting a New Horizon. [PDF]

Front Toxicol, 2020
Patlewicz G.
europepmc   +3 more sources

From QSAR to QSIIR: searching for enhanced computational toxicology models. [PDF]

Methods Mol Biol, 2013
Zhu H.
europepmc   +3 more sources

Introduction to Special Issue: Computational Toxicology [PDF]

Chemical Research in Toxicology, 2021
Nicole C. Kleinstreuer, Igor V. Tetko, Weida Tong   +2 more
openaire   +4 more sources

Decoding per- and polyfluoroalkyl substances (PFAS) in hepatocellular carcinoma: a multi-omics and computational toxicology approach. [PDF]

J Transl Med
Hong Y, Wang D, Liu Z, Chen Y, Wang Y, Li J.   +5 more
europepmc   +2 more sources

Progress in data interoperability to support computational toxicology and chemical safety evaluation. [PDF]

Toxicol Appl Pharmacol, 2019
Watford S, Edwards S, Angrish M, Judson RS, Paul Friedman K.   +4 more
europepmc   +3 more sources

Editorial: Leveraging artificial intelligence and open science for toxicological risk assessment [PDF]

Frontiers in Toxicology
Marc Teunis, Thomas Luechtefeld, Thomas Hartung, Thomas Hartung   +3 more
doaj   +2 more sources

Estimating provisional margins of exposure for data-poor chemicals using high-throughput computational methods

Frontiers in Pharmacology, 2022
Current computational technologies hold promise for prioritizing the testing of the thousands of chemicals in commerce. Here, a case study is presented demonstrating comparative risk-prioritization approaches based on the ratio of surrogate hazard and ...
Chantel I. Nicolas, Matthew W. Linakis, Melyssa S. Minto, Kamel Mansouri, Rebecca A. Clewell, Miyoung Yoon, John F. Wambaugh, Grace Patlewicz, Patrick D. McMullen, Melvin E. Andersen, Harvey J. Clewell III   +10 more
doaj   +1 more source

High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures

npj Systems Biology and Applications, 2021
The ToxCast in vitro screening program has provided concentration-response bioactivity data across more than a thousand assay endpoints for thousands of chemicals found in our environment and commerce.
Jill A. Franzosa, Jessica A. Bonzo, John Jack, Nancy C. Baker, Parth Kothiya, Rafal P. Witek, Patrick Hurban, Stephen Siferd, Susan Hester, Imran Shah, Stephen S. Ferguson, Keith A. Houck, John F. Wambaugh   +12 more
doaj   +1 more source

Casting a wide net: use of diverse model organisms to advance toxicology [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Hahn, M. E., & Sadler, K. C. Casting a wide net: use of diverse model organisms to advance toxicology.
Hahn, Mark E., Sadler, Kirsten C.
core   +1 more source