Results 11 to 20 of about 70,828 (242)
Introduction to Special Issue: Computational Toxicology [PDF]
Chemical Research in Toxicology, 2021 Nicole Kleinstreuer +2 more
openalex +4 more sources
Computational Toxicology [PDF]
Toxicology Mechanisms and Methods, 2008 Luis G. Valerio, Rakesh Dixit
openalex +3 more sources
Predicting molecular initiating events using chemical target annotations and gene expression
BioData Mining, 2022 Background The advent of high-throughput transcriptomic screening technologies has resulted in a wealth of publicly available gene expression data associated with chemical treatments.
Joseph L. Bundy +5 more
doaj +1 more source
A harmonized chemical monitoring database for support of exposure assessments
Scientific Data, 2022 Measurement(s) occurrence of chemicals in environmental and biological media Technology Type(s) mass spectrometry (curation of public data) Sample Characteristic - Organism Homo sapiens • aquatic invertebrates • aquatic vertebrates/mammals • birds • fish
Kristin K. Isaacs +12 more
doaj +1 more source
Annotation depth confounds direct comparison of gene expression across species
BMC Bioinformatics, 2021 Background Comparisons of the molecular framework among organisms can be done on both structural and functional levels. One of the most common top-down approaches for functional comparisons is RNA sequencing. This estimation of organismal transcriptional
Elias Oziolor, Seda Arat, Matthew Martin
doaj +1 more source
Toxics, 2022 With the abundance of chemicals in the environment that could potentially cause neurodevelopmental deficits, there is a need for rapid testing and chemical screening assays.
Kimberly A. Jarema +6 more
doaj +1 more source
npj Systems Biology and Applications, 2021 The ToxCast in vitro screening program has provided concentration-response bioactivity data across more than a thousand assay endpoints for thousands of chemicals found in our environment and commerce.
Jill A. Franzosa +12 more
doaj +1 more source
Artificial intelligence as the new frontier in chemical risk assessment
Frontiers in Artificial Intelligence, 2023 The rapid progress of AI impacts various areas of life, including toxicology, and promises a major role for AI in future risk assessments. Toxicology has shifted from a purely empirical science focused on observing chemical exposure outcomes to a data ...
Thomas Hartung, Thomas Hartung
doaj +1 more source
Casting a wide net: use of diverse model organisms to advance toxicology [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Hahn, M. E., & Sadler, K. C. Casting a wide net: use of diverse model organisms to advance toxicology.
Hahn, Mark E., Sadler, Kirsten C.
core +1 more source
Scientific Reports, 2022 The treatment of diabetes involves the use of herbal plants, attracting interest in their cost-effectiveness and efficacy. An aqueous extract of Persea americana seeds (AEPAS) was explored in this study as a possible therapeutic agent in rats with ...
Oluwafemi Adeleke Ojo +10 more
doaj +1 more source