Results 31 to 40 of about 1,723,253 (280)

Letter to the Editors regarding 10% body weight (gain) change as criterion for the maximum tolerated dose: A critical analysis

, 2023
Department of Pathology and Microbiology University of Nebraska Medical CenterCenter for Computational Toxicology and Exposure Office of Research and Development Environmental Protection AgencyState University of Sao Paulo (UNESP)Department of Chemistry ...
Rietjens, Ivonne M C M, Eisenbrand, Gerhard, Greim, Helmut, Strupp, Christian, Fukushima, Shoji, Berry, Sir Colin L, Weber, Klaus, Cohen, Samuel M., de Camargo, Joao Lauro Viana [UNESP], Corton, J Christopher, Sir Colin L. Berry, Joao Lauro Viana de Camargo, J. Christopher Corton, Gerhard Eisenbrand, Samuel M. Cohen, Klaus Weber, Shoji Fukushima, Ivonne M.C.M. Rietjens, Christian Strupp, Helmut Greim   +19 more
core   +1 more source

Male fathead minnow transcriptomes and associated chemical analytes in the Milwaukee estuary system

Scientific Data, 2022
Measurement(s) transcripts • water chemistry Technology Type(s) RNAseq • GC/MS Factor Type(s) exposure Sample Characteristic - Organism Pimephales promelas Sample Characteristic - Environment estuary system Sample Characteristic - Location Milwaukee, WI,
Natàlia Garcia-Reyero, Mark A. Arick, E. Alice Woolard, Mitchell Wilbanks, John E. Mylroie, Kathleen Jensen, Michael Kahl, David Feifarek, Shane Poole, Eric Randolph, Jenna Cavallin, Brett R. Blackwell, Daniel Villeneuve, Gerald T. Ankley, Edward J. Perkins   +14 more
doaj   +1 more source

Accessing, using, and creating chemical property databases for computational toxicology modeling

, 2012
Toxicity data is expensive to generate, is increasingly seen as precompetitive, and is frequently used for the generation of computational models in a discipline known as computational toxicology.
Williams, Anthony J.,, Ekins, Sean,, Willighagen, Egon L.,, Spjuth, Ola,   +3 more
core   +3 more sources

Modeling and insights into the structural characteristics of drug-induced autoimmune diseases

Frontiers in Immunology, 2022
The incidence and complexity of drug-induced autoimmune diseases (DIAD) have been on the rise in recent years, which may lead to serious or fatal consequences. Besides, many environmental and industrial chemicals can also cause DIAD.
Huizhu Guo, Peitao Zhang, Ruiqiu Zhang, Yuqing Hua, Pei Zhang, Xueyan Cui, Xin Huang, Xiao Li, Xiao Li   +8 more
doaj   +1 more source

Cupressus sempervirens Essential Oil: Exploring the Antibacterial Multitarget Mechanisms, Chemcomputational Toxicity Prediction, and Safety Assessment in Zebrafish Embryos

Molecules, 2022
Nowadays, increasing interest has recently been given to the exploration of new food preservatives to avoid foodborne outbreaks or food spoilage. Likewise, new compounds that substitute the commonly used synthetic food preservatives are required to ...
Sarra Akermi, Slim Smaoui, Khaoula Elhadef, Mariam Fourati, Nacim Louhichi, Moufida Chaari, Ahlem Chakchouk Mtibaa, Aissette Baanannou, Saber Masmoudi, Lotfi Mellouli   +9 more
doaj   +1 more source

AR Activity Model Publication Data

, 2018
Supplemental data files and software for the Androgen receptor model from Kleinstreuer et al. “Development and Validation of a Computational Model for Androgen Receptor Activity”, Chemical Research in Toxicology, vol.
EPA's National Center for Computational Toxicology (5039467)
core   +1 more source

Progress in computational toxicology

Journal of Pharmacological and Toxicological Methods, 2014
A poster in the ToxI division at the ACS held in SF ...
openaire   +2 more sources

Navigating the bridge between wet and dry lab toxicology research to address current challenges with high-dimensional data

Frontiers in Toxicology, 2023
Toxicology research has rapidly evolved, leveraging increasingly advanced technologies in high-throughput approaches to yield important information on toxicological mechanisms and health outcomes. Data produced through toxicology studies are consequently
Alexis Payton, Alexis Payton, Kyle R. Roell, Kyle R. Roell, Meghan E. Rebuli, Meghan E. Rebuli, Meghan E. Rebuli, William Valdar, Ilona Jaspers, Ilona Jaspers, Ilona Jaspers, Ilona Jaspers, Julia E. Rager, Julia E. Rager, Julia E. Rager, Julia E. Rager   +15 more
doaj   +1 more source

Computational Toxicology: An Overview of the Sources of Data and of Modelling Methods

, 2009
Background: Toxicology has the goal of ensuring the safety of humans, animals and the environment. Computational toxicology is an area of active development and great potential. There are tangible reasons for the emerging interest in this discipline from
Nigsch, F, Zmuidinavicius, D, Mitchell, John Blayney Owen, Macaluso, NJM, Mitchell, John Blayney Owen; id_orcid   +4 more
core   +1 more source

OPERA models for predicting physicochemical properties and environmental fate endpoints

Journal of Cheminformatics, 2018
The collection of chemical structure information and associated experimental data for quantitative structure–activity/property relationship (QSAR/QSPR) modeling is facilitated by an increasing number of public databases containing large amounts of useful
Kamel Mansouri, Chris M. Grulke, Richard S. Judson, Antony J. Williams   +3 more
doaj   +1 more source