Results 51 to 60 of about 3,045,461 (301)

Collaborative development of predictive toxicology applications

, 2010
OpenTox provides an interoperable, standards-based Framework for the support of predictive toxicology data management, algorithms, modelling, validation and reporting.
Melagraki, G, Ghosh, I., Tcheremenskaia, O., Alexey Zakharov, Gütlein, M., Afantitis, A, Karwath, A., Helma, C, Wicker Joerg, Lagunin Alexey, Ivelina Nikolova, Poroikov, V., Hardy, B, Douglas, N., Patel, Hitesh, Buchwald, Fabian, Wicker, J., Escher, Sylvia, Hardy, B., Lagunin, A., Helma Christoph, Buchwald, F, Maunz, Andreas, Poroikov Vladimir, Martin Gutlein, Gutlein, Martin, Jeliazkov Vedrin, Girschick, T., Douglas, N, Georgia Melagraki, Jeliazkov, V., Druzhilovsky, Dmitry, Sylvia Escher, Kramer, S, Tcheremenskaia Olga, Melagraki, G., Poroikov, Vladimir, Romualdo Benigni, Benigni, R., Fabian Buchwald, Gallagher, D., Nikolova Ivelina, Filimonov, D, Karwath Andreas, Rautenberg, M., Dmitry Filimonov, Natalia Skvortsova, Tobias Girschick, Jeliazkova, N., Gütlein Martin, Ghosh Indira, Karwath, A, Micha Rautenberg, Nikolova, Ivelina, Filimonov, D., Chawla, Sunil, Filimonov Dmitry, Gallagher, D, Zakharov, A., Rautenberg, Micha, Gloriozova Tatyana, Alexey Lagunin, Indira Ghosh, Surajit Ray, Filimonov, Dmitry, Hardy, Barry J., Girschick Tobias, Lagunin, A, Skvortsova, N, Gloriozova, T., Escher, S, Kramer Stefan, Jeliazkova, N, Girschick, T, Tcheremenskaia, Olga, Vladimir Poroikov, Ray, Surajit, Buchwald Fabian, Sopasakis, P, Antreas Afantitis, Melagraki Georgia, Ray, S, Nina Jeliazkova, Novikov, Sergey, Maunz, A., Joerg Wicker, Skvortsova Natalia, Nicki Douglas, Helma, Christoph, Gutlein, M, Zakharov, A, Girschick, Tobias, Hardy Barry, Karwath, Andreas; id_orcid, Ray Surajit, Andreas Karwath, Hardy, Barry, Druzhilovsky Dmitry, Nikolova, I., Maunz, A, Kramer, S., Tcheremenskaia, O, Sopasakis, P., Nikolova, I, Sopasakis, Pantelis, Jeliazkova Nina, Rautenberg Micha, Patel Hitesh, Druzhilovsky, D., Afantitis, A., Zakharov, Alexey V., Zakharov Alexey, Escher, S., Druzhilovsky, D, Melagraki, Georgia, Douglas, Nicki, Sopasakis, Pantelis; id_orcid, Gloriozova, T, Jeliazkova, Nina, Haralambos Sarimveis, Helma, C., Tatyana Gloriozova, Benigni Romualdo, Patel, H., Sopasakis Pantelis, Skvortsova, Natalia, Rautenberg, M, Afantitis Antreas, Barry Hardy, Pantelis Sopasakis, Gallagher, David, Sarimveis, Haralambos, Karwath, Andreas, Jeliazkov, V, Afantitis, Antreas, Buchwald, F., Benigni, R, Wicker, Joerg, Ray, S., Lagunin, Alexey, Sarimveis, H., Benigni, Romualdo, Kramer, Stefan, Sergey Novikov, Novikov, S., Zakharov, Alexey, Chawla, S., Sarimveis Haralambos, Novikov, S, Stefan Kramer, Ghosh, Indira, Olga Tcheremenskaia, Wicker, Jörg, Novikov Sergey, Escher Sylvia, Vedrin Jeliazkov, Hitesh Patel, Poroikov, V, Chawla, S, Andreas Maunz, Sunil Chawla, Jeliazkov, Vedrin, Patel, H, Gallagher David, Sarimveis, H, Dmitry Druzhilovsky, Wicker, J, Christoph Helma, Chawla Sunil, Maunz Andreas, Ghosh, I, Gloriozova, Tatyana, Douglas Nicki, David Gallagher, Skvortsova, N.   +174 more
core   +1 more source

Progress in computational toxicology

Journal of Pharmacological and Toxicological Methods, 2014
A poster in the ToxI division at the ACS held in SF ...
openaire   +2 more sources

Systems Toxicology of Male Reproductive Development- Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes: Data Associated with Publication

, 2018
Data associated with publication on Systems Toxicology of Male Reproductive Development- Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes.
EPA's National Center for Computational Toxicology (5039467)
core   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Development of Prediction Models for Drug-Induced Cholestasis, Cirrhosis, Hepatitis, and Steatosis Based on Drug and Drug Metabolite Structures

Frontiers in Pharmacology, 2020
Drug-induced liver injury (DILI) is one of the major reasons for termination of drug development. Due to the importance of predicting DILI in early phases of drug development, diverse in silico models have been developed to filter out DILI-causing ...
Hyun Kil Shin, Myung-Gyun Kang, Daeui Park, Daeui Park, Tamina Park, Tamina Park, Seokjoo Yoon, Seokjoo Yoon   +7 more
doaj   +1 more source

AR Activity Model Publication Data

, 2018
Supplemental data files and software for the Androgen receptor model from Kleinstreuer et al. “Development and Validation of a Computational Model for Androgen Receptor Activity”, Chemical Research in Toxicology, vol.
EPA's National Center for Computational Toxicology (5039467)
core   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

OPERA models for predicting physicochemical properties and environmental fate endpoints

Journal of Cheminformatics, 2018
The collection of chemical structure information and associated experimental data for quantitative structure–activity/property relationship (QSAR/QSPR) modeling is facilitated by an increasing number of public databases containing large amounts of useful
Kamel Mansouri, Chris M. Grulke, Richard S. Judson, Antony J. Williams   +3 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Modeling and insights into the structural characteristics of drug-induced autoimmune diseases

Frontiers in Immunology, 2022
The incidence and complexity of drug-induced autoimmune diseases (DIAD) have been on the rise in recent years, which may lead to serious or fatal consequences. Besides, many environmental and industrial chemicals can also cause DIAD.
Huizhu Guo, Peitao Zhang, Ruiqiu Zhang, Yuqing Hua, Pei Zhang, Xueyan Cui, Xin Huang, Xiao Li, Xiao Li   +8 more
doaj   +1 more source