Results 121 to 130 of about 94,743 (307)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Computer-aided drug design approaches applied to screen natural product’s structural analogs targeting arginase in Leishmania spp

, 2023
Haruna Luz Barazorda-Ccahuana, Luis Daniel Goyzueta-Mamani, Mayron Antonio Candia-Puma, Camila S. Freitas, Grasiele de Sousa Vieria Tavares, Daniela P. Lage, Eduardo Antônio Ferraz Coelho, Miguel Á. Chávez‐Fumagalli   +7 more
openalex   +1 more source

Hybrid Expert System for Computer-Aided Design of Ship Thruster Subsystems [PDF]

, 2020
Andrzej Kopczyński
openalex   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Computer Aided Design for 180-degree Flat Fold Origamic Architecture with Lattice-type Cross Sections

, 2003
Jun Mitani, Hiromasa Suzuki
openalex   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

COMPUTER-AIDED DESIGN OF FIXED WING UAV PATH TRACKING SYSTEM

, 2018
А. А. Тунік, M. O. Lavanova
openalex   +1 more source

IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems information for authors [PDF]

, 2015

openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Computer-aided design of carbon nanotubes with the desired bioactivity and safety profiles

, 2016
Denis Fourches, Dongqiuye Pu, Liwen Li, Hongyu Zhou, Qingxin Mu, Gaoxing Su, Bing Yan, Alexander Tropsha   +7 more
openalex   +1 more source