Results 11 to 20 of about 250,479 (123)
Proxy Design: A Method for Involving Proxy Users to Speak on Behalf of Vulnerable or Unreachable Users in Co-Design [PDF]
Information Technology and People, 2023, 2023 Designing digital artifacts is not a linear, straightforward process. This is particularly true when applying a user-centered design approach, or co-design, with users who are unable to participate in the design process. Although the reduced participation of a particular user group may harm the end result, the literature on solving this issue is sparse.
arxiv +1 more source
Reducing the Concepts of Data Science and Machine Learning to Tools for the Bench Chemist
CHIMIA, 2019 Machine Learning and Data Science have enjoyed a renaissance due to the availability of increased computational power and larger data sets. Many questions can be now asked and answered, that previously were beyond our scope.
Richard A. Lewis +3 more
doaj +1 more source
Cell Death and Disease, 2022 Triple-negative breast cancer (TNBC) is a heterogeneous subtype of breast cancer that displays highly aggressive with poor prognosis. Owing to the limited targets and drugs for TNBC clinical therapy, it is necessary to investigate the factors regulating ...
Pengyun Li +12 more
doaj +1 more source
Numerical Simulation of a High-Speed Impact of Metal Plates Using a Three-Fluid Model
Metals, 2021 The process of wave formation at the contact boundary of colliding metal plates is a fundamental basis of explosive welding technology. In this case, the metals are in a pseudo-liquid state at the initial stages of the process, and from a mathematical ...
Petr Chuprov +2 more
doaj +1 more source
Molecules, 2014 A series of 1-aryl-3-(2H-chromen-5-yl)urea and 1-aryl-3-(chroman-5-yl)urea derivatives were designed, synthesized and evaluated for their inhibitory activities towards TNF-α production in lipopolysaccharide-stimulated THP-1 cells.
Xingzhou Li +7 more
doaj +1 more source
Design: One, but in different forms [PDF]
Design Studies 30, 3 (2009) 187-223, 2007 This overview paper defends an augmented cognitively oriented generic-design hypothesis: there are both significant similarities between the design activities implemented in different situations and crucial differences between these and other cognitive activities; yet, characteristics of a design situation (related to the design process, the designers,
arxiv +1 more source
Informatics in Medicine Unlocked, 2021 Tuberculosis (TB) is one of the leading causes of death worldwide. The development of new anti-tubercular drugs is required as resistant strains of M. tuberculosis to various first-line drugs are currently available.
Jakaria Shawon +3 more
doaj
What Do I Need to Design for Co-Design? Supporting Co-design as a Designerly Practice [PDF]
arXiv, 2022 Co-design practices have been used for decades to support participatory engagement in design work. However, despite a wide range of materials that describe the design and commitments of numerous co-design experiences, few descriptions of the knowledge that guides designers when creating these experiences exist.
arxiv
Journal of Combustion, 2018 The work is dedicated to the numerical study of detonation wave initiation and propagation in the variable cross-section axisymmetric channel filled with the model hydrogen-air mixture.
Alexander Lopato, Pavel Utkin
doaj +1 more source
Investigating Design Anti-pattern and Design Pattern Mutations and Their Change- and Fault-proneness [PDF]
arXiv, 2021 During software evolution, inexperienced developers may introduce design anti-patterns when they modify their software systems to fix bugs or to add new functionalities based on changes in requirements. Developers may also use design patterns to promote software quality or as a possible cure for some design anti-patterns.
arxiv