Results 21 to 30 of about 12,080,983 (297)

Computer-aided drug design

open access: yesBMC Chemistry, 2023
AbstractComputer-Aided Drug Design tools are now an indispensable part of drug discovery that have made key contributions to the development of drugs. In this editorial, I briefly provide an overview of CADD emphasizing its potential and invite authors from academia and the pharmaceutical and biotechnology sector to present their research in this ...
openaire   +4 more sources

Computer-Aided Conceptual Design Through TRIZ-based Manipulation of Topological Optimizations [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityIn a recent project the authors proposed the adoption of Optimization Systems [1] as a bridging element between Computer-Aided Innovation (CAI) and PLM to identify geometrical contradictions [2], a particular case of ...
Cascini, G.   +3 more
core   +4 more sources

Computer-Aided Vaccine Design [PDF]

open access: yesHuman Vaccines & Immunotherapeutics, 2013
Vaccines, and their discovery, are topics of singular importance in present-day biomedical science. The discovery of vaccines has hitherto been primarily empirical in nature, and it is only now that this is giving way, albeit very slowly, to a more rational approach, supported and enhanced by computer-based methods.
openaire   +2 more sources

Industrial Environmental Impact Assessment Method Based on Detection of Complex Anomalies in Time Series

open access: yesApplied System Innovation
To minimize the environmental impact of energy enterprises, it is important to promptly identify cases of possible changes in the quality of wastewater generated at power plants, that is, cases of exceeding the maximum permissible concentrations of ...
Elena Safonova   +5 more
doaj   +1 more source

VR as a 3D Modelling Tool in Engineering Design Applications

open access: yesApplied Sciences, 2021
The study aims to explore the usefulness of existing VR 3D modelling tools for use in mechanical engineering. Previous studies have investigated the use of VR 3D modelling tools in conceptual phases of the product development process.
Daria Vlah, Vanja Čok, Uroš Urbas
doaj   +1 more source

Semantic Analysis of Technical Documentation: Systematic Review, Formal Task Definition, and Transformer-Based NER Implementation

open access: yesBig Data and Cognitive Computing
The increasing complexity and volume of technical documentation, including requirements specifications, patents, and engineering reports, create significant challenges for manual analysis and knowledge extraction.
Alexander Echin   +4 more
doaj   +1 more source

Synthesis and Biological Evaluation of Chromenylurea and Chromanylurea Derivatives as Anti-TNF-α agents that Target the p38 MAPK Pathway

open access: yesMolecules, 2014
A series of 1-aryl-3-(2H-chromen-5-yl)urea and 1-aryl-3-(chroman-5-yl)urea derivatives were designed, synthesized and evaluated for their inhibitory activities towards TNF-α production in lipopolysaccharide-stimulated THP-1 cells.
Xingzhou Li   +7 more
doaj   +1 more source

Teachers’ and Students' Attitudes Towards Traditional and Computer Assisted Blended Teaching and Learning Processes in Mechanical Engineering Subjects Area [PDF]

open access: yes, 2010
The effectiveness of traditional teaching-learning process in Computer Aided Design (CAD), Computer Aided Manufacturing CAM and Computer Numerical control CNC (CAD-CAM-CNC) module has been evaluated against recently developed two blended teaching ...
Abdulrasool, Salah Mahdi   +7 more
core   +4 more sources

Numerical Study of Detonation Wave Propagation in the Variable Cross-Section Channel Using Unstructured Computational Grids

open access: yesJournal of Combustion, 2018
The work is dedicated to the numerical study of detonation wave initiation and propagation in the variable cross-section axisymmetric channel filled with the model hydrogen-air mixture.
Alexander Lopato, Pavel Utkin
doaj   +1 more source

Bioprinting of Multimaterials with Computer-aided Design/Computer-aided Manufacturing

open access: yesInternational Journal of Bioprinting, 2020
Multimaterials deposition, a distinct advantage in bioprinting, overcomes material’s limitation in hydrogel-based bioprinting. Multimaterials are deposited in a build/support configuration to improve the structural integrity of threedimensional bioprinted construct.
Lee, Jia Min   +2 more
openaire   +3 more sources

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