Results 21 to 30 of about 1,430,083 (395)
Computer-Aided Design of Antimicrobial Peptides: Are We Generating Effective Drug Candidates?
Frontiers in Microbiology, 2020 Antimicrobial peptides (AMPs), especially antibacterial peptides, have been widely investigated as potential alternatives to antibiotic-based therapies.
M. H. Cardoso +6 more
semanticscholar +1 more source
An Updated Review of Computer-Aided Drug Design and Its Application to COVID-19
BioMed Research International, 2021 The recent outbreak of the deadly coronavirus disease 19 (COVID-19) pandemic poses serious health concerns around the world. The lack of approved drugs or vaccines continues to be a challenge and further necessitates the discovery of new therapeutic ...
A. Gurung +4 more
semanticscholar +1 more source
VR as a 3D Modelling Tool in Engineering Design Applications
Applied Sciences, 2021 The study aims to explore the usefulness of existing VR 3D modelling tools for use in mechanical engineering. Previous studies have investigated the use of VR 3D modelling tools in conceptual phases of the product development process.
Daria Vlah, Vanja Čok, Uroš Urbas
doaj +1 more source
Computer-Aided Vaccine Design [PDF]
Human Vaccines & Immunotherapeutics, 2013 Vaccines, and their discovery, are topics of singular importance in present-day biomedical science. The discovery of vaccines has hitherto been primarily empirical in nature, and it is only now that this is giving way, albeit very slowly, to a more rational approach, supported and enhanced by computer-based methods.
openaire +2 more sources
Molecules, 2016 Ampakine compounds have been shown to reverse opiate-induced respiratory depression by activation of amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptors.
Dian Xiao +6 more
doaj +1 more source
Advances in Applying Computer-Aided Drug Design for Neurodegenerative Diseases
International Journal of Molecular Sciences, 2021 Neurodegenerative diseases (NDs) including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, and Huntington’s disease are incurable and affect millions of people worldwide. The development of treatments for this unmet clinical need
M. Salman +5 more
semanticscholar +1 more source
Determination of critical plane and assessment of fatigue durability for multiaxial cyclic loading and arbitrary shift of phases [PDF]
MATEC Web of Conferences, 2019 An analytical solution for the well-known fatigue criterion proposed by Papadopoulos was obtained. An arbitrary shift of phases was taken into account. Comparison between analytical, numerical solutions with experimental data was made.
Stratula Boris A. +3 more
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Reducing the Concepts of Data Science and Machine Learning to Tools for the Bench Chemist
CHIMIA, 2019 Machine Learning and Data Science have enjoyed a renaissance due to the availability of increased computational power and larger data sets. Many questions can be now asked and answered, that previously were beyond our scope.
Richard A. Lewis +3 more
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IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems, 2020 The IEEE T RANSACTIONS ON C OMPUTER -A IDED D ESIGN OF I NTEGRATED C IRCUITS AND S YSTEMS publishes manuscripts focusing on methods, algorithms, and human-machine interfaces for physical and logical design, including: planning, synthesis, partitioning ...
semanticscholar +1 more source
Computer Aided Aroma Design. I. Molecular knowledge framework [PDF]
, 2008 Computer Aided Aroma Design (CAAD) is likely to become a hot issue as the REACH EC document targets many aroma compounds to require substitution. The two crucial steps in CAMD are the generation of candidate molecules and the estimation of properties ...
Floquet, Pascal +5 more
core +1 more source