Results 81 to 90 of about 1,430,083 (395)
Scientific ReportsEfficient resource forecasting in multi-component application scenarios necessitates comprehensive consideration of inter-component dependencies and resource interaction characteristics.
Guangzhang Cui +3 more
doaj +1 more source
Knitting Skeletons: A Computer-Aided Design Tool for Shaping and Patterning of Knitted Garments [PDF]
ACM Symposium on User Interface Software and Technology, 2019 This work presents a novel interactive system for simple garment composition and surface patterning. Our approach makes it easier for casual users to customize machine-knitted garments, while enabling more advanced users to design their own composable ...
Alexandre Kaspar +2 more
semanticscholar +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Scientific Reports, 2022 Molecular level understanding on the role of viral infections causing cervical cancer is highly essential for therapeutic development. In these instances, systems pharmacology along with multi omics approach helps in unraveling the multi-targeted ...
Murali Aarthy +3 more
doaj +1 more source
Interactive graphical computer-aided design system [PDF]
, 1975 System is used for design, layout, and modification of large-scale-integrated (LSI) metal-oxide semiconductor (MOS) arrays. System is structured around small computer which provides real-time support for graphics storage display unit with keyboard, slave
Edge, T. M.
core +1 more source
Development of a STEP-compliant design and manufacturing framework for discrete sheet metal bend parts [PDF]
, 2016 Metal sheets have the ability to be formed into nonstandard sizes and sections. Displacement-controlled computer numerical control press brakes are used for three-dimensional sheet metal forming.
Ali, Liaqat +8 more
core +2 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Joint Center Estimation Using Single-Frame Optimization: Part 1: Numerical Simulation
Sensors, 2018 The biomechanical models used to refine and stabilize motion capture processes are almost invariably driven by joint center estimates, and any errors in joint center calculation carry over and can be compounded when calculating joint kinematics ...
Eric Frick, Salam Rahmatalla
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Exploratory Landscape Validation for Bayesian Optimization Algorithms
MathematicsBayesian optimization algorithms are widely used for solving problems with a high computational complexity in terms of objective function evaluation. The efficiency of Bayesian optimization is strongly dependent on the quality of the surrogate models of ...
Taleh Agasiev, Anatoly Karpenko
doaj +1 more source