Results 101 to 110 of about 246,738 (311)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Discussion about the Using of Computer Education Assisted System in Acupuncture Education in Japan-Simple Introduction in the Invention of "Channel Point Data Base

open access: yes针刺研究, 1998
Computer is sedlom used in acupuncture education in Japan, because there are not many computers in schools and the teachers in school can't use computers. But today, in highly informal society,computer must be widely used.
小野泰生, 兵头明, 郭义
doaj  

Computer Assisted Learning: Assessment of the Veterinary Virtual Anatomy Education Software IVALA™

open access: yesVeterinary Sciences, 2018
Although cadaveric dissection has historically been the cornerstone of anatomical education, it comes at the cost of some emotional, moral, safety, and environmental concerns.
William Brady Little   +3 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Key Findings from recent literature on Computer-aided Assessment

open access: yes, 2003
A perusal of the literature on Computer-aided Assessment (CAA) yields a rich crop of case studies and ‘should-do’s. This paper gathers together the key findings and common themes found in a search of recent papers published on CAA implementation ...
Conole, G.C., Warburton, W.I.
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Developing a computer assisted education material related to thermochemistry [PDF]

open access: yes, 2008
In this study, computer assisted education (CAE) material was developed according to the Meaningful Learning Theory and its effectiveness on the students' success and their attitudes towards computer and chemistry was researched. The research was applied
Demirdağ, Barış   +2 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Exploring Technology Use in English Pronunciation Instruction: A Systematic Review of Trends and Tools

open access: yesSALEE
The integration of technology into education has reshaped pronunciation instruction, introducing innovative tools like Computer-Assisted Pronunciation Training (CAPT) and speech recognition systems.
Nursyafida, Reni Eka Putri
doaj   +1 more source

Undergraduate paramedic students' attitudes to e-learning: findings from five university programs

open access: yesResearch in Learning Technology, 2011
Computers and computer-assisted instruction are being used with increasing frequency in the area of undergraduate paramedic education. Paramedic students' attitudes towards the use of e-learning technology and computer-assisted instruction have ...
Graham Munro   +6 more
doaj   +1 more source

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