Results 41 to 50 of about 610,754 (289)

Development of flexible education systems for technology students : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Computer Systems Engineering at Massey University [PDF]

open access: yes, 1998
The pressures on educational institutions to keep pace with the changes in educational theory and technology are growing rapidly. There is now more competition between education providers, especially in the tertiary and career training sectors, this has ...
Breen, Vivienne
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Editorial

open access: yesResearch in Learning Technology, 2004
This issue forms a special collection on Computer Assisted Assessment (CAA) and has been produced in conjunction with the International Computer Assisted Assessment Conference (www.caaconference.com offers a free downloadable archive of all previous CAA ...
Gráinne Conole, Myles Danson
doaj   +1 more source

The online computer-assisted translation classroom

open access: yesTranslation and Interpreting : the International Journal of Translation and Interpreting Research, 2020
In the modern translation industry, all actors involved in the translation process communicate and collaborate increasingly – and oftentimes entirely – online using modern computer-assisted translation and project management software solutions.New ...
Viktorija Bilic
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Effects of Word-Processors (CALL) on Iranian EFL University Students' Writing Achievements [PDF]

open access: yesMatn/Pizhūhī-i Adabī, 2005
The potential of computers to support learning and teaching m almost all subject areas is now widely accepted. At ail levels of education computers aid teachers to enrich their learning/teaching environment. In the field of language education, especially
sepideh mas'oodi, esmail faghih
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Future of e-Learning in Medical Education: Current Trend and Future Opportunity [PDF]

open access: yesJournal of Educational Evaluation for Health Professions, 2006
A wide range of e-learning modalities are widely integrated in medical education. However, some of the key questions related to the role of e-learning remain unanswered, such as (1) what is an effective approach to integrating technology into pre ...
Sara Kim
doaj   +1 more source

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