Results 61 to 70 of about 246,738 (311)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Comparing Computer-assisted vs. Face to Face Education on Dietary Adherence among Patients with Myocardial Infarction

حیات, 2011
Background & Aim: Diet adherence is a major issue in cardiovascular diseases control. Patient education could be a valuable strategy for promoting diet adherence. The aim of this study was to compare the effects of computer-assisted vs.
M Mohammady, A Memari, M Shaban, A Mehran, P Yavari, M Salari Far   +5 more
doaj  

MICROTEACHING AS TEACHING STRATEGY OF COMPUTER ASSISTED LANGUAGE LEARNING (CALL) FOR ENGLISH PRE-SERVICE TEACHERS

LET: Linguistics, Literature and English Teaching Journal, 2019
In order to facilitate English pre-service teachers to have ability in integrating technology in the classroom, microteaching is one of teaching strategy solutions.
Badi'atul Azmina, Endang Fauziati, Nur Arifah Drajti   +2 more
doaj   +1 more source

A Survey of Students Participating in a Computer-Assisted Education Programme

International Journal of Research in Education and Science, 2015
This paper mainly examines anthropometric data, data regarding the habits, experiences and attitudes of the students about their tablet/laptop/desktop computer use, in addition to self-reported musculoskeletal discomfort levels and frequencies of students participating in a tablet-assisted interactive education programme.
BİNBOĞA YEL, Elif, KORHAN, Orhan
openaire   +4 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

THE USE OF MULTIMEDIA TECHNOLOGY IN THE INSTRUCTIONAL DELIVERY OF THE COURSE „GARMENT CONSTRUCTION” [PDF]

Annals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2015
Against the backdrop of the rapid change and growth of information and communication technology (ICT), the use of computer technology in education has become an essential requisite.
ALCAZ Olga
doaj  

A unique style of computer‐assisted assessment [PDF]

, 1998
This paper examines a project at the University of Wolverhampton that has been producing its own unique style of computerized test for several years. The tests are all designed to deliver a different set of questions each time they are run, a fact which ...
Mike Thelwall, Thelwall, Mike
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source