Results 41 to 50 of about 10,773,976 (296)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Suggested Strategy for Using the Computer as an Instructional Medium [PDF]

open access: yesJournal of Islamic Studies, 1998
Though we realize the importance of using the computer as an instructional medium, some educational settings did not gain the potential effects that computers promise.
Abdullah AbdulAziz AI-Hadlaq
doaj  

Computer Assisted Aerodynamics Education

open access: yesProcedia - Social and Behavioral Sciences, 2012
AbstractIn engineering education, presentations based on visual object are very important as well as audio presentations. Therefore, one of the ways to teach the quantity and the quality of and physical phenomena is demonstrations through experiments.
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

A Preliminary Design Framework for Motivational Robots in Higher Education Japanese-Language E-Learning: A Theory-Guided Synthesis and Structured Expert Review

open access: yesInformation
Sustaining learner motivation remains a persistent challenge in higher education Japanese-language e-learning, where learners often study with limited social presence and personalized encouragement.
Pengfei Lyu, Wei Xie, Toshio Eisaka
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Editorial

open access: yesResearch in Learning Technology, 2004
This issue forms a special collection on Computer Assisted Assessment (CAA) and has been produced in conjunction with the International Computer Assisted Assessment Conference (www.caaconference.com offers a free downloadable archive of all previous CAA ...
Gráinne Conole, Myles Danson
doaj   +1 more source

The online computer-assisted translation classroom

open access: yesTranslation and Interpreting : the International Journal of Translation and Interpreting Research, 2020
In the modern translation industry, all actors involved in the translation process communicate and collaborate increasingly – and oftentimes entirely – online using modern computer-assisted translation and project management software solutions.New ...
Viktorija Bilic
doaj   +1 more source

Information processing in computer-assisted interventions: 4th international conference, 2013 [PDF]

open access: yes, 2014
Information processing in computer-assisted interventions: 4th international conference ...
Barratt, Dean   +11 more
core   +1 more source

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