Results 41 to 50 of about 607,220 (287)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Цифровая трансформацияThe main methodological problems and strategic goals of work on creating the theory and technology of intelligent computer systems of a new generation are considered.
V. V. Golenkov +2 more
doaj +1 more source
Effect of a Computer-Based Decision Support Intervention on Autism Spectrum Disorder Screening in Pediatric Primary Care Clinics: A Cluster Randomized Clinical Trial [PDF]
, 2019 Importance: Universal early screening for autism spectrum disorder (ASD) is recommended but not routinely performed. Objective: To determine whether computer-automated screening and clinical decision support can improve ASD screening rates in ...
Bauer, Nerissa S. +4 more
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Automatic Detection of Olive Tree Canopies for Groves with Thick Plant Cover on the Ground
Sensors, 2022 Marking the tree canopies is an unavoidable step in any study working with high-resolution aerial images taken by a UAV in any fruit tree crop, such as olive trees, as the extraction of pixel features from these canopies is the first step to build the ...
Sergio Illana Rico +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Summary of researches being performed in the Institute of Mathematics and Computer Science on computer science and information technologies [PDF]
Computer Science Journal of Moldova, 2008 Evolution of the informatization notion (which assumes automation of majority of human activities applying computers, computer networks, information technologies) towards the notion of {\it Global Information Society} (GIS) challenges the determination ...
Artiom Alhazov +9 more
doaj
Method to Increase Dependability in a Cloud-Fog-Edge Environment
Sensors, 2021 Robots can be very different, from humanoids to intelligent self-driving cars or just IoT systems that collect and process local sensors’ information. This paper presents a way to increase dependability for information exchange and processing in systems ...
Ovidiu Petru Stan +6 more
doaj +1 more source