Results 41 to 50 of about 132,284 (292)
Fetch unit design for scalable simultaneous multithreading (ScSMT)
Journal of Computer Science and Technology, 2001 Continuous IC process enhancements make possible to integrate on a single chip the re-sources required for simultaneously executing multiple control flows or threads, exploiting different levels of thread-level parallelism: application-, function-, and ...
Juan Carlos Moure +2 more
doaj
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Control Evaluation in a LVoD System Based on a Peer-to-Peer Multicast Scheme
Journal of Computer Science and Technology, 2008 Providing Quality of Service (QoS) in Video on Demand systems (VoD) is a challenging problem. In this paper, we analyse the fault tolerance on a P2P multicast delivery scheme, called Patch Collaboration Manager / Multicast Channel Distributed Branching ...
Rodrigo Godoi +3 more
doaj
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Energy-Aware Duty Cycle Management for Solar-Powered IoT Devices
SensorsIoT devices with sensors and actuators are frequently deployed in environments without access to the power grid. These devices are battery powered and might make use of energy harvesting if battery lifetime is too limited.
Michael Gerndt +3 more
doaj +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Journal of Computer Science and TechnologyChronic Obstructive Pulmonary Disease (COPD) is a chronic respiratory condition characterized by inflammation and narrowing of the airways, leading to symptoms such as shortness of breath, coughing, and chest tightness.
Mohsen Hallaj Asghar +5 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Automating Risk Analysis of Software Design Models
The Scientific World Journal, 2014 The growth of the internet and networked systems has exposed software to an increased amount of security threats. One of the responses from software developers to these threats is the introduction of security activities in the software development ...
Maxime Frydman +4 more
doaj +1 more source