Results 61 to 70 of about 1,158,587 (297)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Development of a Collaborative Design Tool for Structural Analysis in an Immersive Virtual Environment [PDF]
, 2001 This paper contains the results of an on-going collaborative research effort by the departments of Architecture and Computer Science of Virginia Polytechnic Institute and State University, U.S.A., to develop a computer visualization application for the ...
Bowman, Doug A., Setareh, M., Tumati, P.
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Automating Risk Analysis of Software Design Models
The Scientific World Journal, 2014 The growth of the internet and networked systems has exposed software to an increased amount of security threats. One of the responses from software developers to these threats is the introduction of security activities in the software development ...
Maxime Frydman +4 more
doaj +1 more source
ELASTIC CLOUD COMPUTING ARCHITECTURE AND SYSTEM FOR HETEROGENEOUS SPATIOTEMPORAL COMPUTING [PDF]
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2017 Abstract. Spatiotemporal computation implements a variety of different algorithms. When big data are involved, desktop computer or standalone application may not be able to complete the computation task due to limited memory and computing power. Now that a variety of hardware accelerators and computing platforms are available to improve the performance
openaire +3 more sources
A computer architecture for intelligent machines [PDF]
The Theory of Intelligent Machines proposes a hierarchical organization for the functions of an autonomous robot based on the Principle of Increasing Precision With Decreasing Intelligence.
Lefebvre, D. R., Saridis, G. N.
core +1 more source
Integrating multiple sources to answer questions in Algebraic Topology
, 2010 We present in this paper an evolution of a tool from a user interface for a concrete Computer Algebra system for Algebraic Topology (the Kenzo system), to a front-end allowing the interoperability among different sources for computation and deduction ...
Heras, Jonathan +3 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Design of Low-Power Neuromorphic Architectures for IoT Applications
Journal of EngineeringThe rapid growth of the Internet of Things (IoT) demands computing systems that remain highly intelligent while adhering to tight energy constraints. For always-on edge applications, traditional processors are too power-hungry.
Enji Hashim Ismael
doaj +1 more source