Results 61 to 70 of about 260,987 (350)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Development and tuning framework of master/worker applications

open access: yesJournal of Computer Science and Technology, 2005
Parallel/distributed programming is a complex task that requires a high degree of expertise to fulfill the expectations of high performance computation.
Anna Morajko   +7 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Sorting on architecturally diverse computer systems [PDF]

open access: yesProceedings of the Third International Workshop on High-Performance Reconfigurable Computing Technology and Applications, 2009
Sorting is an important problem that forms an essential component of many high-performance applications. Here, we explore the design space of sorting algorithms in recon-figurable hardware, looking to maximize the benefit associated with high-bandwidth, multiple-port access to memory.
Roger D. Chamberlain, Narayan Ganesan
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An Architecture for e-Learning System with Computational Intelligence [PDF]

open access: yesThe Electronic Library, 2007
PurposeThe purpose of this paper is to introduce a new kind of learning management system: proactive LMS, designed to improve the users' online (inter)actions by providing programmable, automatic and continuous intelligent analyses of the users' behaviours, augmented with appropriate actions initiated by the LMS itself.Design/methodology ...
EL ALAMI, Marc   +2 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A Model-Driven Architecture Approach to the Efficient Identification of Services on Service-oriented Enterprise Architecture [PDF]

open access: yes, 2010
Service-Oriented Enterprise Architecture requires the efficient development of loosely-coupled and interoperable sets of services. Existing design approaches do not always take full advantage of the value and importance of the engineering invested in ...
De Roure, David   +8 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Fetch unit design for scalable simultaneous multithreading (ScSMT)

open access: yesJournal of Computer Science and Technology, 2001
Continuous IC process enhancements make possible to integrate on a single chip the re-sources required for simultaneously executing multiple control flows or threads, exploiting different levels of thread-level parallelism: application-, function-, and ...
Juan Carlos Moure   +2 more
doaj  

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