Results 71 to 80 of about 1,158,587 (297)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Wildland fire risk maps using S2F2M*

open access: yesJournal of Computer Science and Technology, 2005
Wildland fires are a critical natural hazard in many regions of the World. Every year, millions of hectares are burned in Tropical, Boreal and Mediterranean forest, which causes a wide variety of effects, from atmospheric emissions, to soil erosion ...
Germán BIanchini   +5 more
doaj  

Smart Cities: A Systematic Review of Emerging Technologies

open access: yesSmart Cities
In the 21st century, rapid urbanisation has brought both challenges and opportunities. Smart cities have emerged as innovative solutions to meet the complex demands of urban life.
Dante D. Sanchez-Gallegos   +3 more
doaj   +1 more source

Methodology of designing computer ontology of subject discipline by future teachers-engineers

open access: yesCTE Workshop Proceedings, 2019
The article deals with the problem of the methodology of designing computer ontology of the subject discipline by the future teachers-engineers in the field of computer technologies. The scheme of ontology of the subject discipline is presented in which
Ivan M. Tsidylo   +6 more
doaj   +1 more source

Fault tolerant architectures for integrated aircraft electronics systems [PDF]

open access: yes
Work into possible architectures for future flight control computer systems is described. Ada for Fault-Tolerant Systems, the NETS Network Error-Tolerant System architecture, and voting in asynchronous systems are ...
Levitt, K. N.   +2 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Current Trends in Wildfire Detection, Monitoring and Surveillance

open access: yesFire
Wildfires pose severe threats to ecosystems and human settlements, making early detection and rapid response critical for minimizing damage. The adage—“You fight fire in the first second with a spoon of water, in the first minute with a bucket, and in ...
Marin Bugarić   +3 more
doaj   +1 more source

Computational Uses of Philosophical Dialogue Theories

open access: yesInformal Logic, 1996
The research discussed in this paper concerns an investigation of logical dialogue games as a vehicle for enhanced human-computer communication. The need for a dialogue capability in computer systems is argued, and a prima facie case made for dialogue ...
David Moore, Dave Hobbes
doaj   +1 more source

Kriging interpolation over heterogeneous computer architectures and systems

open access: yesGIScience & Remote Sensing, 2013
Heterogeneous computer architectures are the emerging and future trend in computer engineering but lead to major challenges in algorithm redesign and software re-engineering. This article reviews the evolutional trend in hardware advancement and discusses how to utilize multiple modern graphics processing units (GPUs) and central processing units (CPUs)
Xuan Shi, Fei Ye
openaire   +1 more source

Home - About - Disclaimer - Privacy