Results 51 to 60 of about 1,158,587 (297)

Trends in computer system structure and architecture [PDF]

, 1976
Management of Complexity is the overriding concern in the development of modern Data Processing Systems. We observe a split into systems which are used in a computing center, and systems which are used by an individual department. The first class of systems is characterized by general purpose attributes of its structure and features for adaption to a ...
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Control Evaluation in a LVoD System Based on a Peer-to-Peer Multicast Scheme

Journal of Computer Science and Technology, 2008
Providing Quality of Service (QoS) in Video on Demand systems (VoD) is a challenging problem. In this paper, we analyse the fault tolerance on a P2P multicast delivery scheme, called Patch Collaboration Manager / Multicast Channel Distributed Branching ...
Rodrigo Godoi, Porfidio Hernández Budé, Emilio Luque Fadón, Xiaoyuan Yang   +3 more
doaj  

The Immune System: the ultimate fractionated cyber-physical system

, 2013
In this little vision paper we analyze the human immune system from a computer science point of view with the aim of understanding the architecture and features that allow robust, effective behavior to emerge from local sensing and actions.
Talcott, Carolyn
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Energy-Aware Duty Cycle Management for Solar-Powered IoT Devices

Sensors
IoT devices with sensors and actuators are frequently deployed in environments without access to the power grid. These devices are battery powered and might make use of energy harvesting if battery lifetime is too limited.
Michael Gerndt, Mustafa Ispir, Isaac Nunez, Shajulin Benedict   +3 more
doaj   +1 more source

Computer Analysis of Architecture Using Automatic Image Understanding

, 2019
In the past few years, computer vision and pattern recognition systems have been becoming increasingly more powerful, expanding the range of automatic tasks enabled by machine vision.
Li, Yuan, Shamir, Lior, Wei, Fan
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

An Agent-Based "Virtual Clinical Trial" for the Analysis and Evaluation of COPD Patients Cohorts Behavior

Journal of Computer Science and Technology
Chronic Obstructive Pulmonary Disease (COPD) is a chronic respiratory condition characterized by inflammation and narrowing of the airways, leading to symptoms such as shortness of breath, coughing, and chest tightness.
Mohsen Hallaj Asghar, Alvaro Wong, Francisco Epelde, Manel Taboada, Dolores Rexachs, Emilio Luque   +5 more
doaj   +1 more source

Universal computation by multi-particle quantum walk [PDF]

, 2012
A quantum walk is a time-homogeneous quantum-mechanical process on a graph defined by analogy to classical random walk. The quantum walker is a particle that moves from a given vertex to adjacent vertices in quantum superposition.
A. M. Childs, Bakr, Bromberg, Childs, Chuang, D. Gosset, Hoffman, Karski, Mizel, Perets, Peruzzo, Sansoni, Z. Webb   +12 more
core   +1 more source