Results 171 to 180 of about 3,000,211 (229)

Enhancing Evidence Generation by Linking Randomized Clinical Trials to Real‐World Data: The INVESTED‐Medicare Linkage Study

Clinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho, HoJin Shin, Mehdi Najafzadeh, Brian Claggett, Janinne Ortega‐Montiel, Jun Liu, Julie M. Paik, Narlina F. Lalani, Marie C. Bradley, John Concato, Scott D. Solomon, Orly Vardeny, Elisabetta Patorno   +12 more
wiley   +1 more source

Constructing an External Control Arm Using the French REALYSA Cohort to Replicate Outcomes of a Randomized Trial Arm in Advanced Hodgkin Lymphoma

Clinical Pharmacology &Therapeutics, EarlyView.
External control (EC) arms using routine data can be used as comparators in clinical trials under certain conditions. The objective of this study was to assess the ability of an EC arm to replicate outcomes of a randomized controlled trial (RCT) arm receiving the same treatment strategy in advanced stage classical Hodgkin lymphoma and serve as ...
Olivia Febvey‐Combes, Cédric Rossi, Behrouz Kassai, Tesla Murairi Mirimo, Loïc Chartier, Fanny Cherblanc, Emeline Cugnod, Hervé Ghesquières, Aurélien Belot   +8 more
wiley   +1 more source

Exposure‐Response Analyses of Datopotamab Deruxtecan (Dato‐DXd), a TROP2‐Directed Antibody‐Drug Conjugate, in Advanced Non‐small Cell Lung Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Exposure‐response analyses supported a favorable benefit‐risk profile of Dato‐DXd at 6 mg/kg Q3W in patients with advanced nonsquamous NSCLC. Datopotamab deruxtecan (Dato‐DXd) is a trophoblast cell‐surface antigen‐2 (TROP2)‐directed antibody‐drug conjugate (ADC) that has demonstrated clinical activity in patients with NSCLC who have received prior ...
Ying Hong, Anna M. Mc Laughlin, Yuzhuo Pan, Sofia Friberg Hietala, Sophie Peigné, Michael Chargualaf, Zoey Tang, Diansong Zhou, Naoyuki Tajima, Malaz Abutarif, Tushar Garimella   +10 more
wiley   +1 more source

Beyond the Human Negotiator: Generative AI and the Threshold of Autonomous Decision‐Making

Conflict Resolution Quarterly, EarlyView.
ABSTRACT This article provides a comprehensive framework for understanding the role of artificial intelligence (AI) in negotiation, evaluating contemporary systems through the specific case study of Large Language Models (LLMs). To address the lack of established terminology, it first proposes a new typology distinguishing Negotiation Supported by AI ...
Martin Svatos
wiley   +1 more source

Symposium on Computer Animation 2008

Graphical Models, 2009
openaire   +1 more source

I Have a Medical Degree. Should I Consider a Career in Clinical Pharmacology in 2026?

Clinical Pharmacology &Therapeutics, EarlyView.
Jean Terrier
wiley   +1 more source

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Computer animation

Proceedings of the 2nd annual conference on Computer graphics and interactive techniques - SIGGRAPH '75, 1975
A comprehensive 3-D real-time computer animation system is based upon a broad range of research activities in the field of computer graphics. In many ways the requirements for such a system are more challenging and complex than for other graphics systems.
openaire   +3 more sources

Computational manga and anime

SIGGRAPH Asia 2013 Courses, 2013
Traditional manga (comic) and anime (cartoon) creation are painstaking processes. Even computers are utilized for the content creation, computers are mainly utilized as a naive digital canvas. With the increasing computing power and decreasing cost of CPU & GPU, more computing resource can be exploited cost-effectively for intelligent and semi ...
Tien-Tsin Wong, Takeo Igarashi, Ying-Qing Xu, Danqing Shi   +3 more
openaire   +1 more source

Computer animation in Portugal

Computers & Graphics, 1989
Abstract In this paper we will describe the Portuguese traditional and computer animation market. Research and Development activities will also be covered, with special attention to the work done at INESC. Animation paradigms will be described. The major features of the CLICK animation system, currently under development, will be described with some ...
Pedro Faria Lopes, Mário Rui Gomes
openaire   +1 more source

Experiments with computer animation

Proceedings of the 3rd annual conference on Computer graphics and interactive techniques, 1976
Three generally accepted facts are:1. Computers are getting cheap and fast enough to do cost-effective graphics on line and in real time;2. The future of computer graphics is in raster scan;3. Computer animation is emerging as a volatile art form and as a medium for scientific communication.Concurrently, we find computer animation somewhat polluted and
Nicholas Negroponte, Paul Pangaro
openaire   +1 more source