Results 101 to 110 of about 4,598,340 (299)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

University of Melbourne, School of Architecture : design 2, 1964

open access: yes, 1964
Cover titleUniversity of Melbourne, School of Architecture -- coverIncomplete, contains no student work - some pages left empty [not all ...
University of Melbourne. Faculty of Architecture
core  

University Computer Center Newsletter (November 1968)

open access: yes, 1968
Announcements; Literature; Software; FORTRAN Input/Output; Arith Errors; Computer Control PersonnelThis item in the historical Computing & Communications News collection was contributed by the University Information Technology Services (UITS) at the ...
University of Arizona Computer Center
core   +4 more sources

Automatic Generation of Simulators for Processors Enhanced for Security in Virtualization

open access: yesIEEE Access
All new computer architectures need to be performance evaluated for acceptance and simulation is the most widely used method for evaluation of new processor designs.
Swapneel C. Mhatre, Priya Chandran
doaj   +1 more source

Continuum computer architecture for exaflops computation [PDF]

open access: yesCommunications of the ACM, 2001
The ultimate computers in our long-term future will deliver exaflops-scale performance (or greater) and will look very different from today’s micro-processors and massively parallel computers. Ironically, however, their alien structures and operational behavior can be inferred from the same technology trends driving development of today’s conventional
openaire   +3 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Software architecture visualisation [PDF]

open access: yes, 2004
Tracing the history of software engineering reveals a series of abstractions. In early days, software engineers would construct software using machine code.
Hatch, Andrew
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Business process and software architecture model co-evolution patterns [PDF]

open access: yes, 2012
Software systems are subject to change. To embrace change, the systems should be equipped with automated mechanisms. Business process and software architecture models are two artifacts that are subject to change in an interrelated manner that requires ...
Pooyan Jamshidi (5276344)   +5 more
core   +2 more sources

MB-CNN: Memristive Binary Convolutional Neural Networks for Embedded Mobile Devices

open access: yesJournal of Low Power Electronics and Applications, 2018
Applications of neural networks have gained significant importance in embedded mobile devices and Internet of Things (IoT) nodes. In particular, convolutional neural networks have emerged as one of the most powerful techniques in computer vision, speech ...
Arjun Pal Chowdhury   +2 more
doaj   +1 more source

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