Results 81 to 90 of about 5,114,447 (358)

An integrated taxonomy of standard indicators for ranking and selecting supercomputers

IET Computers & Digital Techniques, 2023
Due to the ever‐increasing computing requirements of modern applications, supercomputers are at the centre of attraction as a platform for high‐performance computing.
Davood Maleki, Alireza Mansouri, Ehsan Arianyan   +2 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Improving the Delay of Residue-to-Binary Converter for a Four-Moduli Set

Advances in Electrical and Computer Engineering, 2011
The residue number system (RNS) is an unconventional number system which can be used to achieve high-performance hardware implementations of special-purpose computation systems such as digital signal processors.
MOLAHOSSEINI, A. S.
doaj   +1 more source

Event‐based high throughput computing: A series of case studies on a massively parallel softcore machine

IET Computers & Digital Techniques, 2023
This paper introduces an event‐based computing paradigm, where workers only perform computation in response to external stimuli (events). This approach is best employed on hardware with many thousands of smaller compute cores with a fast, low‐latency ...
Mark Vousden, Jordan Morris, Graeme McLachlan Bragg, Jonathan Beaumont, Ashur Rafiev, Wayne Luk, David Thomas, Andrew Brown   +7 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

A Detailed Study of SOT-MRAM as an Alternative to DRAM Primary Memory in Multi-Core Environment

IEEE Access
As the current primary memory technology is reaching its limits, it is essential to explore alternative memory technologies to accommodate modern applications and use cases.
H. D. Kallinatha, Sadhana Rai, Basavaraj Talawar   +2 more
doaj   +1 more source

Applying Slicing Technique to Software Architectures [PDF]

Proceedings of the 4th IEEE International Conference on Engineering of Complex Computer Systems, pp.87-98, August 1998, 2001
Software architecture is receiving increasingly attention as a critical design level for software systems. As software architecture design resources (in the form of architectural specifications) are going to be accumulated, the development of techniques and tools to support architectural understanding, testing, reengineering, maintenance, and reuse ...
arxiv  

Evolving Neural Architecture Using One Shot Model [PDF]

arXiv, 2020
Neural Architecture Search (NAS) is emerging as a new research direction which has the potential to replace the hand-crafted neural architectures designed for specific tasks. Previous evolution based architecture search requires high computational resources resulting in high search time. In this work, we propose a novel way of applying a simple genetic
arxiv  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Differentiable Neural Architecture Transformation for Reproducible Architecture Improvement [PDF]

arXiv, 2020
Recently, Neural Architecture Search (NAS) methods are introduced and show impressive performance on many benchmarks. Among those NAS studies, Neural Architecture Transformer (NAT) aims to improve the given neural architecture to have better performance while maintaining computational costs. However, NAT has limitations about a lack of reproducibility.
arxiv