Results 41 to 50 of about 266,906 (297)

The Future of e-Learning in Medical Education: Current Trend and Future Opportunity [PDF]

Journal of Educational Evaluation for Health Professions, 2006
A wide range of e-learning modalities are widely integrated in medical education. However, some of the key questions related to the role of e-learning remain unanswered, such as (1) what is an effective approach to integrating technology into pre ...
Sara Kim
doaj   +1 more source

PENGARUH PENERAPAN COMPUTER ASSISTED INSTRUCTION TERHADAP PRESTASI BELAJAR SISWA SMP PADA PEMBELAJARAN FISIKA [PDF]

, 2014
Telah dilakukan penelitian mengenai penerapan Computer Assisted Instruction yang bertujuan untuk mengetahui apakah terdapat perbedaan prestasi belajar antara siswa yang melakukan pembelajaran fisika dengan menerapkan Computer Assisted Instruction dan ...
Saepulloh, Aep
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The Effectiveness of Computer-Assisted Instruction in Developmental Mathematics [PDF]

, 2010
This quasiexperimental study compared academic performance of students enrolled in a developmental mathematics course using traditional instruction (i.e., lecture) and traditional instruction supplemented with computer-assisted instruction.
Ackerman, Beth, Spradlin, Kathy Dye
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Computer-based programs on acquisition of reading skills in schoolchildren (review of contemporary foreign investigations) [PDF]

Современная зарубежная психология, 2015
The article presents a description of 17 computer-based programs, which were used over the last 5 years (2008—2013) in 15 studies of computer-assisted reading instruction and intervention of schoolchildren.
Prikhoda N.A.
doaj  

PENGGUNAAN MODEL PEMBELAJARAN COMPUTER ASSISTED INSTRUCTION (CAI) UNTUK MENINGKATKAN MOTIVASI DAN HASIL BELAJAR SISWA DI KELAS VIII-E RSBI SMP NEGERI 1 CIREBON [PDF]

, 2012
Mala Dwi Arianti: PENGGUNAAN MODEL PEMBELAJARAN COMPUTER ASSISTED INSTRUCTION (CAI) UNTUK MENINGKATKAN MOTIVASI DAN HASIL BELAJAR DI KELAS VIII-E RSBI SMP NEGERI 1 CIREBON Pembelajaran aktif merupakan suatu pembelajaran yang mengajak siswa untuk ...
Mala Dwi Arianti,
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source