Results 41 to 50 of about 60,920 (260)

Computing solutions for matching games [PDF]

International Journal of Game Theory, 2011
This paper studies matching games. A matching game is a cooperative game \((N, v)\) defined on a graph \(G = (N, E)\) with \(n=|N|\) vertices, \(m=|E|\) edges, and an edge weighting \(w : E \rightarrow {\mathbb R}_+\). The player set is \(N\) and the value of a coalition \(S\subseteq N\) is defined as the maximum weight of a matching in the subgraph ...
Péter Biró 0001, Walter Kern, Daniël Paulusma   +2 more
openaire   +5 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

VR Scene Detail Enhancement Method Based on Depth Reinforcement Learning Algorithm

International Journal of Computational Intelligence Systems
In virtual reality, due to factors such as light sources and surface materials of objects, the details of the scene exhibit extremely complex changes, making it difficult to capture environmental modeling relationships and reducing the quality of scene ...
Changbao Feng, Xin Tong, Meili Zhu, Feng Qu   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

PENGARUH KEERGONOMISAN STASIUN KOMPUTER GAME NET PADA RISIKO GANGGUAN OTOT-RANGKA

J@ti Undip: Jurnal Teknik Industri, 2018
Abstrak Maraknya pengguna online game memicu terjadinya peningkatan jumlah penyedia jasa bermain game net dengan pengguna anak-anak, namun stasiun komputer yang digunakan ditujukan untuk pengguna dewasa.
Yassierli Yassierli, Diaz Abdul Aziiz Irawan, Kartika Kusuma Pratiwi   +2 more
doaj   +1 more source

Game Control Methods Comparison when Avoiding Collisions with Multiple Objects Using Radar Remote Sensing

Remote Sensing, 2020
This article formulates the concept of games in the field of process control theory in marine sciences and reviews the literature on the possible applications of games. The possible types of game control processes for moving objects are presented.
Józef Lisowski
doaj   +1 more source

Computer games with intelligence

10th IEEE International Conference on Fuzzy Systems. (Cat. No.01CH37297), 2002
Artificial Intelligence (AI) is playing an increasingly important role in the success or failure of computer games. The paper explores the use of AI in games focusing on difficulties faced by game developers and techniques that have proven useful. An argument is presented for the value of collaboration between the game and academic AI communities.
Johnson, D. M., Wiles, J. H.
openaire   +5 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Development of a computer-based cognitive training game and usage feasibility with Thai stroke patients

Journal of Associated Medical Sciences, 2022
Background: Cognitive impairments are common sequelae found in patients after a stroke event, leading them to necessitate long-term care. Currently, there are two common cognitive approaches, namely conventional intervention, and technology-based ...
Patchanee Tungjan, Riccardo Corrado, Peeraya Munkhetvit   +2 more
doaj   +1 more source