Results 51 to 60 of about 60,920 (260)

Computing Game Values for Crash Games [PDF]

open access: yes, 2007
We consider crash games which are a generalization of parity games in which the play value of a play is an integer, -∞ or ∞. In particular, the play value of a finite play is given as the sum of the payoffs of the moves of the play. Accordingly, one player aims at maximizing the play value whereas the other player aims at minimizing this value. We show
Thomas Gawlitza, Helmut Seidl
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Designing Tommy and Pokina Educative Language Game Software: a Transnational Popular Culture Project

open access: yesSISFORMA, 2019
Products of popular culture are many. One of those is educative language game software. Not only is a game useful in combating boredom, but a game can increase someone’s education capability.
Ekawati Marhaenny Dukut   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Going to school in World of Warcraft. Observations from a trial programme using off-the-shelf computer games as learning tools in secondary education

open access: yesDesigns for Learning, 2009
The use of commercial, off-the-shelf computer games as teaching tools is an interesting possibility, but one that may alter the teacher’s role. Unlike specially adapted, game-like educational software, students’ attitudes toward the learning potential of
Mats Wiklund, Love Ekenberg
doaj   +1 more source

Evolutionary games and computer simulations. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1993
The Prisoner's Dilemma has long been considered the paradigm for studying the emergence of cooperation among selfish individuals. Because of its importance, it has been studied through computer experiments as well as in the laboratory and by analytical means. However, there are important differences between the way a system composed of many interacting
Huberman, Bernardo A.   +1 more
openaire   +4 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Relationship between Computer Game Addiction and Body Mass Index and Sleep Habits of 10 to 12 Years Old Primary School Students in Hamadan

open access: yesپژوهان, 2021
Background and Objective: Computer game addiction may cause health problems, such as changes in body mass index and sleep disorders for children and adolescents.
Fatemeh Cheraghi   +3 more
doaj  

Representation of Cultural Ideologies in Computer Games [PDF]

open access: yesمطالعات رسانه‌های نوین, 2015
This article aims to study the representation of cultural values in computer games.We conducted a semiotic analysis on three computer games sponsored by three Iranian state organizations.
Hadi khaniki, Mahya Barekat
doaj   +1 more source

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