Results 101 to 110 of about 3,233,093 (388)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Efficient workflow scheduling using an improved multi-objective memetic algorithm in cloud-edge-end collaborative framework

open access: yesScientific Reports
With the rapid advancement of large-scale model technologies, AI agent frameworks built on foundation models have become a central focus of artificial-intelligence research.
Guangzhang Cui   +3 more
doaj   +1 more source

Design and implementation of virtual reality instructional tools for 3D printing processes in digital manufacturing [PDF]

open access: yesJournal of Intelligent Manufacturing and Special Equipment
Purpose – In order to allow easy replication of this study, industry standard software that is easily attainable was used. Most of the programs used are free to download, and the ones that are not are available, students can still obtain them through ...
Daniel Cubillos, Magesh Chandramouli
doaj   +1 more source

Broadening the interface bandwidth in simulation based training [PDF]

open access: yes
Currently most computer based simulations rely exclusively on computer generated graphics to create the simulation. When training is involved, the method almost exclusively used to display information to the learner is text displayed on the cathode ray ...
Somers, Larry E.
core   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Computer graphics for metaverse

open access: yesVirtual Reality & Intelligent Hardware, 2022
Nadia Magnenat Thalmann   +4 more
doaj   +1 more source

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