Results 101 to 110 of about 735,370 (319)

Graphical Object Detection in Document Images [PDF]

open access: yesICDAR 2019, 2020
Graphical elements: particularly tables and figures contain a visual summary of the most valuable information contained in a document. Therefore, localization of such graphical objects in the document images is the initial step to understand the content of such graphical objects or document images. In this paper, we present a novel end-to-end trainable
arxiv  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Design and implementation of virtual reality instructional tools for 3D printing processes in digital manufacturing [PDF]

open access: yesJournal of Intelligent Manufacturing and Special Equipment
Purpose – In order to allow easy replication of this study, industry standard software that is easily attainable was used. Most of the programs used are free to download, and the ones that are not are available, students can still obtain them through ...
Daniel Cubillos, Magesh Chandramouli
doaj   +1 more source

Attribute-conditioned Layout GAN for Automatic Graphic Design [PDF]

open access: yesarXiv, 2020
Modeling layout is an important first step for graphic design. Recently, methods for generating graphic layouts have progressed, particularly with Generative Adversarial Networks (GANs). However, the problem of specifying the locations and sizes of design elements usually involves constraints with respect to element attributes, such as area, aspect ...
arxiv  

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

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