Results 91 to 100 of about 2,661,670 (316)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

IMPLEMENTASI PROTOKOL TCP/IP UNTUK PENGENDALIAN KOMPUTER JARAK JAUH

open access: yesJurnal Informatika, 2002
This day, computer networking has become important necessity for data exchange between computers. And along with the growing of number of computer in a network, the difficulty for managing that network also increased.
Rudy Adipranata
doaj  

Network optimization by regional computing for UAVs' big data

open access: yesFrontiers in Computer Science
Unmanned Aerial Vehicles (UAVs) are increasingly used in sectors such as surveillance, agriculture, and disaster response, generating massive volumes of real-time big data. Traditional cloud computing introduces high latency, while edge computing suffers
Afzal Badshah   +5 more
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Network traffic anomalies identification based on classification methods / Tinklo srauto anomalijų identifikavimas, taikant klasifikavimo metodus

open access: yesMokslas: Lietuvos Ateitis, 2015
A problem of network traffic anomalies detection in the computer networks is analyzed. Overview of anomalies detection methods is given then advantages and disadvantages of the different methods are analyzed. Model for the traffic anomalies detection was
Donatas Račys, Dalius Mažeika
doaj   +1 more source

Local area networking: Ames centerwide network [PDF]

open access: yes
A computer network can benefit the user by making his/her work quicker and easier. A computer network is made up of seven different layers with the lowest being the hardware, the top being the user, and the middle being the software.
Price, Edwin
core   +1 more source

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