Results 121 to 130 of about 1,267,704 (337)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

GBSS:researches on group-based semantic search

open access: yesTongxin xuebao, 2006
A group-based semantic search method-GBSS was presented.With regard to architecture,GBSS introduced a hybrid architecture in which the storage and search of raw data was based on DHT network,but the storage and search of meta-data was based on ...
CHEN Hai-tao   +2 more
doaj  

Network Inference in Public Administration: Questions, Challenges, and Models of Causality [PDF]

open access: yesarXiv
Descriptive and inferential social network analysis has become common in public administration studies of network governance and management. A large literature has developed in two broad categories: antecedents of network structure, and network effects and outcomes.
arxiv  

Tucker Decomposition Network: Expressive Power and Comparison [PDF]

open access: yesarXiv, 2019
Deep neural networks have achieved a great success in solving many machine learning and computer vision problems. The main contribution of this paper is to develop a deep network based on Tucker tensor decomposition, and analyze its expressive power. It is shown that the expressiveness of Tucker network is more powerful than that of shallow network. In
arxiv  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Research on Architecture and Energy-Saving Mechanism of Reconfigurable Flexible Network

open access: yesDianxin kexue, 2013
With the development of network service and the expanding of network size, there are many problems of expandability and energy consumption in current network.
Wanwei Huang   +3 more
doaj  

Efficient Quantum Transforms [PDF]

open access: yesarXiv, 1997
Quantum mechanics requires the operation of quantum computers to be unitary, and thus makes it important to have general techniques for developing fast quantum algorithms for computing unitary transforms. A quantum routine for computing a generalized Kronecker product is given. Applications include re-development of the networks for computing the Walsh-
arxiv  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Closure to “Improved Design of Fluid Networks with Computers” [PDF]

open access: bronze, 1968
Thomas A. Marlow   +3 more
openalex   +1 more source

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