Results 91 to 100 of about 2,050,944 (292)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Building epidemic models for living populations and computer networks. [PDF]
Sci Prog, 2021 Kondakci S, Kondakci DD.
europepmc +1 more source
Object-oriented Tools for Distributed Computing [PDF]
, 1993 Distributed computing systems are proliferating, owing to the availability of powerful, affordable microcomputers and inexpensive communication networks.
Adler, Richard M.
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Diffusion of Confidential Information on Networks [PDF]
, 2011 This is a natural generalization of the previous work by Dan, "Modeling and Simulation of Diffusion Phenomena on Social Networks," to appear in The proceedings of 2011 Third International Conference on Computer Modeling and Simulation.
Dan, Yuya
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
IEEE AccessThe rapid development of Internet-connected devices has driven the rise of smart cities, where large-scale Internet of Things (IoT) systems require efficient infrastructure management with centralized monitoring and control.
Bao Pham-Thai +3 more
doaj +1 more source
Computing on the Edge of the Network.
, 2021 To enable fifth generation cellular communication network (5G) systems, energy efficient architectures are required that can provide a reliable service platform for the delivery of 5G services and beyond. Device Enhanced Edge Computing is a derivative of Multi-Access Edge Computing (MEC), which provides computing and storage resources directly on the ...
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source