Results 101 to 110 of about 5,327,416 (306)
Enabling global multimedia distributed services based on hierarchical DHT overlay networks [PDF]
, 2008 Providing innovating multimedia services is a high priority for service providers. Due to the high traffic volume created by multimedia content, the use of decentralised services can lead to better solutions.
Carmen Guerrero +12 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Building epidemic models for living populations and computer networks. [PDF]
Sci Prog, 2021 Kondakci S, Kondakci DD.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
IEEE AccessThe rapid development of Internet-connected devices has driven the rise of smart cities, where large-scale Internet of Things (IoT) systems require efficient infrastructure management with centralized monitoring and control.
Bao Pham-Thai +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Traffic weaver: Semi-synthetic time-varying traffic generator based on averaged time series
SoftwareXTraffic Weaver is a Python package developed to generate a semi-synthetic signal (time series) with finer granularity, based on averaged time series, in a manner that, upon averaging, closely matches the original signal provided.
Piotr Lechowicz +3 more
doaj +1 more source
An adaptive algorithm for solving cell loss unfairness problem in ATM networks
, 2012 [[abstract]]In ATM networks, using coding matrix technique to compensate consecutive cell loss caused by buffer overflow is widely discussed recently. This technique do much reduce the cell loss probability.
Y.-C. Wang;C.-C. Lu
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source