Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
The Picasso's skepticism on computer science and the dawn of generative AI: questions after the answers to keep "machines-in-the-loop". [PDF]
Pesapane F, Cuocolo R, Sardanelli F.
europepmc +1 more source
Stereotypical descriptions of computer science career interests are not representative of many computer scientists. [PDF]
McChesney JE, Behrend TS, Glosenberg A.
europepmc +1 more source
A computer science curriculum for a liberal arts college [PDF]
R. Waldo Roth
openalex +1 more source
Using Rasch KIDMAP to identify whether China dominates the research area of computer science (CS) based on the specialization index of article citations: Bibliometric analysis. [PDF]
Yen PT, Chien TW, Chou W, Kan WC.
europepmc +1 more source
Effect of laboratory facilities on computer science curriculum [PDF]
R. Brien Maguire, Lawrence R. Symes
openalex +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Early Childhood Preservice Teachers' Perceptions of Computer Science, Gender Stereotypes, and Coding in Early Childhood Education. [PDF]
Ari F, Arslan-Ari I, Vasconcelos L.
europepmc +1 more source
An experience component for undergraduate computer science education [PDF]
Herbert L. Dershem
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source