Results 261 to 270 of about 10,928,440 (381)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Analysis of co-authorship networks among Brazilian graduate programs in computer science. [PDF]
PLoS One, 2022 Nunes da Silva A +3 more
europepmc +1 more source
Individualized instruction in computer science [PDF]
, 1974 Robert R. Korfhage, Robert J. Smith
openalex +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Dataset of computer science course queries from students: Categorized and scored according to Bloom's taxonomy. [PDF]
Data BriefZaman KAU, Islam A, Islam YM, Sayed MA.
europepmc +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
What is a first-year computer science graduate student? [PDF]
, 1976 Stephen W. Smoliar
openalex +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
What Employers Look For In Hiring Computer Science Graduates (Panel Discussion) [PDF]
, 1978 Robert F. Bartell +3 more
openalex +1 more source
Math/CompSci Newsletter, Fall 2008 [PDF]
, 2008 Department of Mathematics and Computer Science, Bridgewater State College
core +1 more source