Results 81 to 90 of about 9,853,002 (405)

Computer Simulations [PDF]

open access: yes, 1985
This paper examines the various uses of simulation for education and training which involve the exploitation of the computer for the running of all or part of the simulation. The development of this form of simulation can be seen as a part of the growth in computer based training (CBT) in \ud recent years, which has been given renewed impetus by recent
openaire   +1 more source

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

open access: yesFEBS Open Bio, Volume 15, Issue 6, Page 940-948, June 2025.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya   +3 more
wiley   +1 more source

An adaptive variational algorithm for exact molecular simulations on a quantum computer [PDF]

open access: yesNature Communications, 2018
Quantum simulation of chemical systems is one of the most promising near-term applications of quantum computers. The variational quantum eigensolver, a leading algorithm for molecular simulations on quantum hardware, has a serious limitation in that it ...
Harper R. Grimsley   +3 more
semanticscholar   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

Computer simulation of a novel pharmaceutical silicon nanocarrier

open access: yesNanotechnology, Science and Applications, 2010
Saeed Soltani, Soroush Sardari, Sima Azadi SororDrug Design and Bioinformatics Unit, Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, IranAbstract: We show the potential of the nanosilicon structure of ...
Saeed Soltani   +2 more
doaj  

Optimal control strategy of COVID-19 spread in Morocco using SEIRD model

open access: yesMoroccan Journal of Pure and Applied Analysis, 2021
This paper aims to predict the development of the COVID-19 pandemic in Morocco from a mathematical approach. Based on the reliability of the data and the nature of confirmed cases, the SEIRD model is employed to provide a theoretical framework to ...
Ferjouchia H.   +3 more
doaj   +1 more source

Transportation Centrality: Quantifying the Relative Importance of Nodes in Transportation Networks Based on Traffic Modeling

open access: yesIEEE Access, 2023
The topology of transportation networks such as road and rail networks determines the efficiency and effectiveness of the corresponding transport systems. Quantifying the relative importance of nodes of such networks is vital to understand their dynamics.
Mahendra Piraveenan   +1 more
doaj   +1 more source

Comparison of the cost‐effectiveness of a computer‐assisted learning program with a tutored demonstration to teach intestinal motility to medical students [PDF]

open access: yes, 1995
Computer‐based simulations of undergraduate experiments in pharmacology and physiology may offer a cost‐effective alternative to the traditional live laboratory for some students, for whom laboratory skills are less important.
Dewhurst, D. G., Leathard, H. L.
core   +2 more sources

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

open access: yesAging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Scheduling Algorithms for a Hybrid Flow Shop under Uncertainty

open access: yesAlgorithms, 2020
In modern production systems, scheduling problems have to be solved in consideration of frequently changing demands and varying production parameters.
Christin Schumacher, Peter Buchholz
doaj   +1 more source

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