Results 111 to 120 of about 74,223 (272)

Diacetylene‐Functionalized Glycan Mimetics for Receptor‐Mediated Cluster Imprinting in Model Membranes

open access: yesMacromolecular Rapid Communications, EarlyView.
Diacetylene‐containing glycan mimetics cluster upon selective lectin binding in GUVs. Subsequent irradiation leads to the formation of fluorescent polymer clusters, while non‐clustered glycan mimetics remain unaffected in the membrane. ABSTRACT The glycocalyx, a dense layer of glycoproteins and glycolipids on eukaryotic cells, is essential for cellular
Luca‐Cesare Blawitzki   +5 more
wiley   +1 more source

YTHDF1 shapes immune-mediated hepatitis via regulating inflammatory cell recruitment and response

open access: yesGenes and Diseases
Severe immune responses regulate the various clinical hepatic injuries, including autoimmune hepatitis and acute viral hepatitis. N6-methyladenosine (m6A) modification is a crucial regulator of immunity and inflammation.
Hao Li   +9 more
doaj   +1 more source

Controlled method of reducing electrophoretic mobility of macromolecules, particles, or cells [PDF]

open access: yes, 1992
A method of reducing electrophoretic mobility of macromolecules, particles, cells, and other substances is provided which comprises interacting in a conventional electrophoretic separating procedure, the substances with a polymer-linked affinity compound
Vanalstine, James M.
core   +1 more source

Formation of bacterial streamers during filtration in microfluidic systems [PDF]

open access: yes, 2012
Bacterial behavior during filtration is complex and is influenced by numerous factors. The aim of this paper is to report on experiments designed to make progress in the understanding of bacterial transfer in filters and membranes.
Bacchin, Patrice   +3 more
core   +2 more sources

Morphological Modification of Metal Oxide Nanomaterials Using Different Types of Organic Modifiers

open access: yesChemistryOpen, EarlyView.
The study reveals the interaction between organic modifiers and metal oxide nanoparticles to tune the structure for improving final applications. Organic modifiers make incorporating nanoparticles into composite components easier, improving their optical, mechanical, and electrical characteristics.
Taskiya Akter   +5 more
wiley   +1 more source

Andrias Davidianus Peptide Hydrogel Enables Sustained SR9011 Release to Promote Efferocytosis and Alleviate Colitis

open access: yesSmall, EarlyView.
NR1D1 suppresses epithelial CD47 transcription to promote efferocytosis by macrophages. In UC, NR1D1 expression is diminished, leading to CD47 upregulation, inhibition of apoptotic cell clearance, and exacerbation of intestinal inflammation. Restoring rhythmic NR1D1 activation using SR9011‐loaded bioadhesive hydrogel enhances efferocytosis, improves ...
Yidong Chen   +7 more
wiley   +1 more source

Adenine Nucleotides Attenuate Murine T Cell Activation Induced by Concanavalin A or T Cell Receptor Stimulation

open access: yesFrontiers in Pharmacology, 2018
Extracellular ATP and its metabolites affect various cellular immune responses, including T cell function, but there are apparently conflicting reports concerning the effects of adenine nucleotides on T cells.
Yuria Shinohara, Mitsutoshi Tsukimoto
doaj   +1 more source

TRPM7 Deficiency Accelerates Vascular Senescence by Inhibiting H3K18 Lactylation

open access: yesAging Cell, EarlyView.
TRPM7 deficiency reduces lactate production in endothelial cells and downregulates both p300 expression and nuclear translocation. These changes collectively lead to decreased H3K18 lactylation levels. Consequently, this downregulates genes vital for vascular homeostasis while upregulating genes associated with aging and vascular remodeling (including ...
Yue Wang   +9 more
wiley   +1 more source

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