Results 61 to 70 of about 22,621,819 (277)

Mannosyltransferase (GPI-14) overexpression protects promastigote and amastigote forms of Leishmania braziliensis against trivalent antimony

open access: yesParasites & Vectors, 2019
Background Glycosylphosphatidylinositol is a surface molecule important for host-parasite interactions. Mannosyltransferase (GPI-14) is an essential enzyme for adding mannose on the glycosylphosphatidyl group.
Christiana Vargas Ribeiro   +4 more
doaj   +1 more source

Murine brain endothelial cells differently modulate interferon-γ and interleukin-17 production in vitro [PDF]

open access: yesArchives of Biological Sciences, 2009
Brain endothelial cells (BEC) are the major constituents of the blood-brain barrier (BBB), the structure that controls entrance of immune cells into CNS parenchyma.
Momčilović Miljana   +2 more
doaj   +1 more source

Acetylcholine Receptors and Concanavalin A-Binding Sites on Cultured Xenopus Muscle Cells: Electrophoresis, Diffusion, and Aggregation [PDF]

open access: yes, 1988
Using digitally analyzed fluorescence videomicroscopy, we have examined the behavior of acetylcholine receptors and concanavalin A binding sites in response to externally applied electric fields.
Fraser, Scott E., Stollberg, Jes
core  

Order independent structural alignment of circularly permuted proteins

open access: yes, 2004
Circular permutation connects the N and C termini of a protein and concurrently cleaves elsewhere in the chain, providing an important mechanism for generating novel protein fold and functions.
Binkowski, T. Andrew   +2 more
core   +1 more source

Extraction and Purification of Laccases from Rice Stems

open access: yesBio-Protocol, 2019
Laccases are found in cell walls of plants in very low amounts. This protocol provides an efficient method to purify laccases from rice stems. The method involves three steps: 1) Isolation of total protein from rice stems using buffers with high salt ...
Chenna Swetha, Padubidri Shivaprasad
doaj   +1 more source

Circular RNAs associated with a mouse model of concanavalin A‐induced autoimmune hepatitis: preliminary screening and comprehensive functional analysis

open access: yesFEBS Open Bio, 2020
Without treatment, autoimmune hepatitis (AIH) often leads to cirrhosis, liver failure and, in some cases, death. However, the pathogenesis of AIH remains incompletely understood.
Yang Liu   +5 more
doaj   +1 more source

The development of a purification procedure for Peptide:n-Glycosidase A from Prunus amygdalus : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

open access: yes, 1997
Peptide-N4-acetyl-β-glucosaminyl) asparagine amidases cleave the amide bond between N-linked glycans at N-acetylglucosamine and asparagine, liberating intact oligosaccharide chains from glycoproteins. Although PNGase A is commonly used by glycobiologists
Diepen, Angela Corinne van
core  

Microarray‐based transcriptional profiling of a mouse model of autoimmune hepatitis

open access: yesFEBS Open Bio, 2020
Long noncoding RNAs (lncRNAs) are RNA molecules longer than 200 nucleotides that do not typically code for a protein. lncRNAs have regulatory roles in many physiological processes, and their dysregulation can contribute to cancer, cardiovascular and ...
Yang Liu   +5 more
doaj   +1 more source

Berbamine and thymoquinone exert protective effects against immune-mediated liver injury via NF-κB dependent pathway

open access: yesFrontiers in Veterinary Science, 2022
BackgroundImmune-mediated hepatitis is a severe impendence to human health, and no effective treatment is currently available. Therefore, new, safe, low-cost therapies are desperately required.
Sarmed H. Kathem   +2 more
doaj   +1 more source

In Vivo Expression of Interleukin-37 Reduces Local and Systemic Inflammation in Concanavalin A-Induced Hepatitis

open access: yesTheScientificWorldJournal, 2011
We recently reported that after LPS stimulation, IL-37 translocates to the nucleus and reduces the expression of proinflammatory cytokines. The aim of this study was to investigate whether transiently expressed IL-37 in mice reduces inflammation in ...
Ana-Maria Bulau   +6 more
semanticscholar   +1 more source

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