Results 61 to 70 of about 75,255 (281)
The effect of concanavalin A on the replication of rotavirus (SA-11) in cell culture
Brazilian Archives of Biology and Technology, 2002 Rotavirus (RV) strain SA-11 was studied with respect to its infectivity in MA-104 cell cultures and the effect of concanavalin A (ConA). Receptors for ConA at the surface of MA-104 cell were determined by fluorescence assay and specifically inhibited by ...
Hasenack Beatriz S. +7 more
doaj
Computational insights into the circular permutation roles on ConA binding and structural stability
Current Research in Structural BiologyThe mechanisms behind Concanavalin A (ConA) circular permutation have been under investigation since 1985. Although a vast amount of information is available about this lectin and its applications, the exact purpose of its processing remains unclear.
Vinicius J.S. Osterne +5 more
doaj +1 more source
Frontiers in Plant Science, 2016 The Closterium peracerosum–strigosum–littorale (C. psl.) complex is the best characterized charophycean alga with respect to the processes of sexual reproduction.
Jun Abe +4 more
doaj +1 more source
Microarray‐based transcriptional profiling of a mouse model of autoimmune hepatitis
FEBS Open Bio, 2020 Long noncoding RNAs (lncRNAs) are RNA molecules longer than 200 nucleotides that do not typically code for a protein. lncRNAs have regulatory roles in many physiological processes, and their dysregulation can contribute to cancer, cardiovascular and ...
Yang Liu +5 more
doaj +1 more source
PK/PD Modeling of the PDE7 Inhibitor—GRMS-55 in a Mouse Model of Autoimmune Hepatitis
Pharmaceutics, 2021 This study aimed to assess the efficacy and explore the mechanisms of action of a potent phosphodiesterase (PDE)7A and a moderate PDE4B inhibitor GRMS-55 in a mouse model of autoimmune hepatitis (AIH).
Artur Świerczek +4 more
doaj +1 more source
Effect of synthetic and bovine milk conjugated linoleic acid (CLA) on immune function : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutrition Science at Massey University [PDF]
, 1999 CLA is a collective name for a mixture of positional and geometrical isomers of linoleic acid (c-9, c-12-octadecadioenic acid) which possess conjugated double bonds.
Zhao, Hui
core
Advanced Science, EarlyView.Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang +12 more
wiley +1 more source
Artificial Cells, Nanomedicine, and Biotechnology, 2019 The aim of present study was to develop the efficient targeting of Concanavalin-A conjugated nanotransfersomal gel to bind directly to melanocytes gel layer against UVB induced skin carcinoma.
Manmohan S. Jangdey +2 more
doaj +1 more source
Frontiers in Veterinary Science, 2022 BackgroundImmune-mediated hepatitis is a severe impendence to human health, and no effective treatment is currently available. Therefore, new, safe, low-cost therapies are desperately required.
Sarmed H. Kathem +2 more
doaj +1 more source
Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]
, 2015 Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam +3 more
core +3 more sources