Results 91 to 100 of about 9,785,422 (274)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Behavioral Determinants of Childhood Obesity in the United States: An Exploratory Study

open access: yesJournal of Obesity
Childhood obesity is a complex and multifactorial phenomenon. Understanding these factors is crucial in developing effective interventions to prevent and treat childhood obesity.
Soumitra Palit   +4 more
doaj   +1 more source

Elemental composition of thalli of the lichen Cladоnia stellaris under air pollution

open access: yesTransactions of the Karelian Research Centre of the Russian Academy of Sciences, 2016
The elemental composition of Cladonia lichens in areas affected by the Murmansk Region metal processing industry was investigated. Abnormally high levels of heavy metals (Cu, Ni, Fe) were detected in lichens under this impact.
Tatyana Sukhareva
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Solar Concentrators

open access: yesInternational Journal of Applied Sciences, 2010
Solar technology offers great potential in terms of supplying the world's energy needs. However, its current contribution to the world is still limited. The main factor is related to high initial cost of building the system. This paper will provide an up-to-date review of solar concentrators and their benefits to make solar technology affordable.
Muhammad-Sukki, Firdaus   +4 more
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A Proposal for Key Sustainability Credit Assessment Criteria to Update and Develop International Ranking Systems for Green Buildings [PDF]

open access: yesصفه, 2017
As they are mainly focused on the environmental side of sustainability, a concentration on green certificates’ credit systems risks neglecting the bigger picture.
Maryam Mollazadeh Yazdani
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

High concentration insulin

open access: yesIndian Journal of Endocrinology and Metabolism, 2018
This communication reviews available high concentration insulins and their basic as well as clinical pharmacology. It classifies all high concentration insulins, and describes their pharmacokinetic and pharmacodynamic properties. The article discusses the utility of high concentrations insulins, lists indications for these preparations, highlights ...
openaire   +3 more sources

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